Adhesion G Protein-Coupled Receptor G5 (ADGRG5) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor G5 (ADGRG5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324351
tested applications
ELISA, WB, IF/ICC
Description
GPR114 Antibody is a Rabbit Polyclonal against GPR114.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor G5 (ADGRG5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/5000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IZF4 |
| Gene ID | 221188 |
| Alias | ADGRG5,PGR27,GPR114,Gm1109,UNQ2524/PRO6017 |
| Background | Antibody anti-ADGRG5 |
| Status | RUO |
Descripción
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG5, also known as GPR114, is expressed in immune cells such as eosinophils and has a role in modulating immune responses. It is particularly involved in allergic inflammation, contributing to immune cell adhesion and migration. ADGRG5 is under investigation for its potential role in asthma and other allergic disorders. Its specific signaling pathways are not fully elucidated, but its immune-related functions make it a promising target for therapies in allergic and inflammatory conditions.
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