Adhesion G Protein-Coupled Receptor G2 (ADGRG2) Antibody

260€ (50 µl)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor G2 (ADGRG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx210326
tested applications
ELISA, IHC
Description
GPR64 Antibody is a Rabbit Polyclonal against GPR64.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Adhesion G Protein-Coupled Receptor G2 (ADGRG2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8IZP9 |
Gene ID | 10149 |
Alias | ADGRG2,GPR64,HE6,TM7LN2,CBAVDX, EDDM6 |
Background | Antibody anti-ADGRG2 |
Status | RUO |
Descripción
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG2, or GPR64, is predominantly expressed in the male reproductive tract, particularly in the epididymis, and is thought to regulate sperm maturation. It also exhibits expression in other tissues, such as the kidney, suggesting broader physiological roles. ADGRG2 contributes to fluid absorption and regulation of ciliary activity. Dysregulation of ADGRG2 has been linked to male infertility and potential roles in kidney function. Research is ongoing to uncover its signaling pathways and therapeutic potential.
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