Family main features
Induced myeloid leukemia cell differentiation protein Mcl-1 is a member of the Bcl-2 family of proteins, which play a crucial role in the regulation of apoptosis. Mcl-1 was initially identified due to its upregulation during the differentiation of myeloid leukemia cells. It is encoded by the MCL1 gene, which is located on chromosome 1q21. This protein is highly expressed in various tissues, including the heart, lungs, and liver, and is involved in promoting cell survival by inhibiting apoptosis. Mcl-1 is an essential protein for normal development, tissue homeostasis, and the immune response.
Mcl-1 is classified as an anti-apoptotic member of the Bcl-2 family. This family is divided into three main groups based on function:
Mcl-1 is a vital anti-apoptotic protein within the Bcl-2 family, essential for cellular survival, immune function, and development. Its ability to inhibit apoptosis by interacting with pro-apoptotic proteins underscores its importance in maintaining cellular homeostasis. However, dysregulation of Mcl-1, particularly its overexpression, is associated with various cancers and resistance to treatment, making it a significant target for therapeutic intervention. Understanding the regulation and function of Mcl-1 is crucial for developing strategies to modulate apoptosis in disease contexts.
Induced myeloid leukemia cell differentiation protein Mcl-1
BCL2L3,EAT,MCL1-ES,MCL1L,MCL1S Mcl-1, M,bcl2-L-3,mcl1/EAT,Bcl-2-like protein 3,BCL2L3,Bcl-2-related protein EAT/mcl1
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con MCL1 apoptosis regulator
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | MCL1 | abx519389 | Dog Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit | Dog | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8HYS5 | RUO | ||
FineTest | MCL1 | EH2099 | Human MCL1(Induced myeloid leukemia cell differentiation protein Mcl-1) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 31.25-2000pg/ml | 96T | Q07820 | RUO | ||
Abbexa | MCL1 | abx251430 | Human Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 531.25 | 96 tests | Q07820 | RUO |
Abbexa | MCL1 | abx493797 | Human Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.127 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MCL1 | abx152287 | Human Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | Q07820 | RUO |
Abbexa | MCL1 | abx595369 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Cell ELISA Kit | Human | Cell ELISA | 493.75 | 96 tests | Q07820 | RUO | |||
Abbexa | MCL1 | abx493798 | Mouse Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) CLIA Kit | Mouse | Serum, plasma, tissue homogenates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.063 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MCL1 | abx154362 | Mouse Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | MCL1 | abx519392 | Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 6.25 U/ml - 400 U/ml | 1.8 U/ml | 687.5 | 96 tests | Q9Z1P3 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | MCL1 | FNab05053 | anti- MCL1 antibody | human | monoclonal | Mouse | myeloid cell leukemia sequence 1(BCL2-related) | IgG2a | Unconjugated | ELISA, WB, IF, IHC | 100µg | Q07820 | RUO | |
FineTest | MCL1 | FNab05052 | anti- MCL1 antibody | human | polyclonal | Rabbit | myeloid cell leukemia sequence 1 (BCL2-related) | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q07820 | RUO | |
FineTest | MCL1 | FNab05054 | anti- MCL1L-specific antibody | human | polyclonal | Rabbit | myeloid cell leukemia sequence 1(BCL2-related) | IgG | Unconjugated | ELISA, IHC | 100µg | Q07820 | RUO | |
Abbexa | MCL1 | abx314397 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Biotin | ELISA | 162.5 | 20 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx235053 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Monoclonal | Mouse | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx011122 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Monoclonal | Mouse | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 362.5 | 100 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx431424 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Goat | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | MCL1 | abx270291 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | FCM | 300 | 50 tests | RUO | ||
Abbexa | MCL1 | abx128848 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx302446 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx314395 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (HRP) | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | HRP | ELISA | 162.5 | 20 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx412627 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB | 462.5 | 100 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx173651 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Monoclonal | Mouse | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC, IF/ICC | 787.5 | 1 ml | RUO | ||
Abbexa | MCL1 | abx314396 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (FITC) | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | FITC | 162.5 | 20 µg | Q07820 | RUO | ||
Abbexa | MCL1 | abx325125 | Induced Myeloid Leukemia Cell Differentiation Protein Phospho-Ser159 (MCL1 pS159) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein Phospho-Ser159 (MCL1 pS159) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx000635 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx235052 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx326267 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx327608 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx113912 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx235054 | MCL1L-specific Antibody | Human | Polyclonal | Rabbit | MCL1L-specific | Unconjugated | ELISA, IHC | 350 | 100 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx125365 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Monoclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC | 212.5 | 20 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx013136 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC | 43.75 | 10 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx241677 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx328856 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q07820 | RUO | |
Abbexa | MCL1 | abx241678 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Human | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q07820 | RUO | |
Abbexa | MCL1 | abx105556 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (Biotin) | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Biotin | ELISA | 162.5 | 20 µg | P97287 | RUO | |
Abbexa | MCL1 | abx108394 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (HRP) | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | HRP | ELISA | 162.5 | 20 µg | P97287 | RUO | |
Abbexa | MCL1 | abx129693 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | P97287 | RUO | |
Abbexa | MCL1 | abx109908 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | ELISA | 162.5 | 20 µg | P97287 | RUO | |
Abbexa | MCL1 | abx106973 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody (FITC) | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | FITC | 162.5 | 20 µg | P97287 | RUO | ||
Abbexa | MCL1 | abx000718 | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody | Mouse | Polyclonal | Rabbit | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) | Unconjugated | WB, IF/ICC | 175 | 20 µl | Q07820 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | MCL1 | P5674 | Recombinant Human MCL1 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q07820 | RUO | ||
Abbexa | MCL1 | abx166839 | Human Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | RUO | |
Abbexa | MCL1 | abx167434 | Mouse Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | RUO | |
Abbexa | MCL1 | abx262540 | Human Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Protein | Human | Recombinant | E. coli | Unconjugated | SDS-PAGE | 225 | 2 µg | Q07820 | RUO |
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