Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit

Este producto es parte de MCL1 apoptosis regulator
Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx519392
Tested Applications
ELISA

Description

Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Induced Myeloid Leukemia Cell Differentiation Protein (MCL1)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
6.25 U/ml - 400 U/ml
Sensitivity
1.8 U/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9Z1P3
Alias
BCL2L3,EAT,MCL1-ES,MCL1L,MCL1S Mcl-1, M,bcl2-L-3,mcl1/EAT,Bcl-2-like protein 3,BCL2L3,Bcl-2-related protein EAT/mcl1
Background
Elisa Kits for: MCL1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Induced myeloid leukemia cell differentiation protein MCL1 is an anti-apoptotic protein that plays a critical role in regulating cell survival, particularly in hematopoietic and immune cells Mcl-1 belongs to the Bcl-2 family and helps prevent apoptosis by interacting with pro-apoptotic Bcl-2 family members, inhibiting their activity and preventing mitochondrial outer membrane permeabilization Mcl-1 is essential for the survival of various cell types, including myeloid cells, and its expression is tightly regulated during cell differentiation and immune responses Its dysregulation has been linked to cancer, particularly hematological malignancies, where overexpression of Mcl-1 promotes the survival of malignant cells and contributes to chemotherapy resistance In addition to its role in apoptosis, Mcl-1 is involved in regulating mitochondrial function, cell metabolism, and the stress response Mcl-1’s central role in both cell survival and apoptosis makes it a critical factor in normal cellular function and a potential target for therapeutic intervention in cancer and other diseases related to cell survival regulation

Productos relacionados

abx000635

Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

MCL1 Antibody is a Rabbit Polyclonal antibody against MCL1. This gene encodes an anti-apoptotic protein, which is a memb…

Ver producto
abx000718

Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

MCL1 Antibody is a Rabbit Polyclonal antibody against MCL1. This gene encodes an anti-apoptotic protein, which is a memb…

Ver producto
abx011122

Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in express…

Ver producto