Family main features
ABTB (Ankyrin Repeat and BTB/POZ Domain Containing Protein) belongs to a family of proteins characterized by the presence of ankyrin repeats and a BTB/POZ (Broad-Complex, Tramtrack, and Bric-a-Brac/Poxvirus and Zinc finger) domain. These proteins are involved in diverse cellular processes, including transcriptional regulation, chromatin remodeling, protein-protein interactions, and signal transduction. Ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops, first discovered in signaling proteins in yeast Cdc10 and Drosophila Notch. Domains consisting of ankyrin tandem repeats mediate protein–protein interactions and are among the most common structural motifs in known proteins. They appear in bacterial, archaeal, and eukaryotic proteins, but are far more common in eukaryotes. Ankyrin repeat proteins, though absent in most viruses, are common among poxviruses. Most proteins that contain the motif have four to six repeats. BTB/POZ domain The BTB domain is a protein-protein interaction module is often found at the N-termini of several zinc finger transcription factors and Shaw-type potassium channel proteins. Appears to be implicate in regulating gene expression through the local control of chromatin conformation. ABTB2 encodes a protein with an ankyrin repeat region and two BTB/POZ domains.Proteins containing both these domains may function as scaffolds for protein complexes or as regulators of gene expression. They are often implicated in development, differentiation, and disease processes.
ABTB proteins share common structural features:
The ABTB family encompasses multiple members, each with distinct structural and functional characteristics. Examples include:
ABTB proteins participate in various cellular processes:
ABTB proteins interact with a wide range of binding partners:
Dysregulation of ABTB proteins can have implications for human health and disease:
The ABTB family of proteins, characterized by the presence of ankyrin repeats and a BTB/POZ domain, plays diverse roles in cellular processes, including transcriptional regulation, chromatin remodeling, and signal transduction. Through their interactions with transcription factors, chromatin-modifying enzymes, and signaling molecules, ABTB proteins influence gene expression programs and cellular functions essential for development, homeostasis, and disease. Dysregulation of ABTB proteins is associated with various pathological conditions, including cancer, developmental disorders, and neurological diseases, highlighting their importance in cellular physiology and human health.
Ankyrin Repeat And BTB/POZ Domain Containing Protein(ABTB1)
BPOZ,BPOZ-2,BTB3,BTBD21
Ankyrin Repeat And BTB/POZ Domain Containing Protein(ABTB2)
ABTB2A,BTBD22
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con ABTB - Ankyrin Repeat And BTB/POZ Domain Containing Protein
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Esta página contiene 13 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | ABTB1 | abx385563 | Human Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q969K4 | RUO |
Abbexa | ABTB2 | abx500578 | Human Ankyrin repeat and BTB/POZ domain-containing protein 2 (ABTB2) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8N961 | RUO | ||
Abbexa | ABTB1 | abx500576 | Mouse Ankyrin repeat and BTB/POZ domain-containing protein 1 (ABTB1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q99LJ2 | RUO | ||
Abbexa | ABTB2 | abx500579 | Mouse Ankyrin repeat and BTB/POZ domain-containing protein 2 (ABTB2) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q7TQI7 | RUO | ||
Abbexa | ABTB1 | abx500577 | Rat Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q5XIU1 | RUO | ||
Abbexa | ABTB2 | abx500580 | Rat Ankyrin repeat and BTB/POZ domain-containing protein 2 (ABTB2) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | O08764 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ABTB1 | abx309323 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | Unconjugated | ELISA | 162.5 | 20 µg | Q969K4 | RUO | |
Abbexa | ABTB1 | abx309326 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | Biotin | ELISA | 162.5 | 20 µg | Q969K4 | RUO | |
Abbexa | ABTB1 | abx037995 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ABTB1 | abx029410 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | Unconjugated | ELISA, WB | 250 | 80 µl | Q969K4 | RUO | |
Abbexa | ABTB1 | abx309325 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (FITC) | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | FITC | 162.5 | 20 µg | Q969K4 | RUO | ||
Abbexa | ABTB1 | abx309324 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (HRP) | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | HRP | ELISA | 162.5 | 20 µg | Q969K4 | RUO | |
Abbexa | ABTB1 | abx110983 | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody | Human | Polyclonal | Rabbit | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q969K4 | RUO |
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