Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (FITC)

Este producto es parte de ABTB - Ankyrin Repeat And BTB/POZ Domain Containing Protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx309325

Description

ABTB1 Antibody (FITC) is a Rabbit Polyclonal against ABTB1 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q969K4
Gene ID
80325
NCBI Accession
NP_115937.1, NM_032548.3, NP_742024.1, NM_172027.2
OMIM
608308
Alias
BPOZ,BPOZ-2,BTB3,BTBD21
Background
Antibody anti-ABTB1
Status
RUO

Descripción

ABTB1 is a multifunctional protein characterized by ankyrin repeat and BTB/POZ domains, which facilitate protein-protein interactions and contribute to its role as an adaptor in cellular signaling pathways. It is involved in regulating processes such as cell proliferation, apoptosis, and differentiation by interacting with key signaling molecules, including those in the tumor suppressor p53 pathway. ABTB1 is widely expressed in various tissues and is thought to modulate transcriptional responses and cellular stress reactions. It has been implicated in the regulation of cellular growth and survival, particularly under conditions of oxidative stress or DNA damage. Dysregulation of ABTB1 has been linked to cancer progression and other disorders involving disrupted signaling pathways. Its ability to interact with multiple partners highlights its importance as a molecular scaffold in maintaining cellular homeostasis.
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