Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (Biotin)
169€ (20 µg)
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Name
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx309326
Tested Applications
ELISA
Description
ABTB1 Antibody (Biotin) is a Rabbit Polyclonal against ABTB1 conjugated to Biotin.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Immunogen: Recombinant human Ankyrin repeat and BTB/POZ domain-containing protein 1 protein (1-243AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q969K4 |
| Gene ID | 80325 |
| NCBI Accession | NP_115937.1, NM_032548.3, NP_742024.1, NM_172027.2 |
| OMIM | 608308 |
| Alias | BPOZ,BPOZ-2,BTB3,BTBD21 |
| Background | Antibody anti-ABTB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABTB1 is a multifunctional protein characterized by ankyrin repeat and BTB/POZ domains, which facilitate protein-protein interactions and contribute to its role as an adaptor in cellular signaling pathways. It is involved in regulating processes such as cell proliferation, apoptosis, and differentiation by interacting with key signaling molecules, including those in the tumor suppressor p53 pathway. ABTB1 is widely expressed in various tissues and is thought to modulate transcriptional responses and cellular stress reactions. It has been implicated in the regulation of cellular growth and survival, particularly under conditions of oxidative stress or DNA damage. Dysregulation of ABTB1 has been linked to cancer progression and other disorders involving disrupted signaling pathways. Its ability to interact with multiple partners highlights its importance as a molecular scaffold in maintaining cellular homeostasis.
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