Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029410
tested applications
ELISA, WB
Description
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q969K4 |
| Alias | BPOZ,BPOZ-2,BTB3,BTBD21 |
| Background | Antibody anti-ABTB1 |
| Status | RUO |
Descripción
ABTB1 is a multifunctional protein characterized by ankyrin repeat and BTB/POZ domains, which facilitate protein-protein interactions and contribute to its role as an adaptor in cellular signaling pathways. It is involved in regulating processes such as cell proliferation, apoptosis, and differentiation by interacting with key signaling molecules, including those in the tumor suppressor p53 pathway. ABTB1 is widely expressed in various tissues and is thought to modulate transcriptional responses and cellular stress reactions. It has been implicated in the regulation of cellular growth and survival, particularly under conditions of oxidative stress or DNA damage. Dysregulation of ABTB1 has been linked to cancer progression and other disorders involving disrupted signaling pathways. Its ability to interact with multiple partners highlights its importance as a molecular scaffold in maintaining cellular homeostasis.
Related Products
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq].
Ver Producto
Ankyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody
Rabbit Polyclonal against the ABTB1 protein.
Ver ProductoAnkyrin Repeat And BTB/POZ Domain Containing Protein 1 (ABTB1) Antibody
Ankyrin Repeat And Btb (Poz) Domain Containing 1 Antibody is a Rabbit Polyclonal antibody against Ankyrin Repeat And Btb (Poz) Domain Containing 1.
Ver Producto