Family main features
ACTA1 encodes for actin alpha 1, a protein that is a key component of the thin filaments in skeletal muscle. ACTA1 is a protein that plays a crucial role in muscle formation and function. Its expression is induced by various stimuli and conditions that promote muscle development. In response to these stimuli, committed cells such as satellite cells undergo fusion to form myotubes, which eventually mature into muscle fibers. The expression of skeletal alpha actin is not only a hallmark of muscle formation but also serves as a trigger for the expression of other "myogenic genes." These genes are essential for the intricate process of muscle development and include factors involved in myoblast differentiation, fusion, and maturation. Therefore, the expression of ACTA1 is pivotal in orchestrating the molecular events necessary for the formation and maintenance of skeletal muscle tissue. The regulation of ACTA1 expression is tightly controlled and is influenced by various signaling pathways and transcription factors involved in muscle development and regeneration. Dysregulation of ACTA1 expression or mutations in the ACTA1 gene can lead to muscle disorders and myopathies, highlighting the critical role of skeletal alpha actin in muscle biology and physiology.
Actin alpha 1 has a highly conserved structure characterized by:
Actin proteins are classified into several isoforms based on their tissue distribution:
ACTA1 specifically refers to the alpha actin isoform expressed in skeletal muscle.
ACTA1 plays several critical roles in skeletal muscle function:
ACTA1 interacts with a variety of proteins and molecular pathways:
Mutations in ACTA1 can lead to several skeletal muscle disorders:
ACTA1 encodes actin alpha 1, a protein essential for the structure and function of skeletal muscle. It forms the thin filaments of muscle fibers, interacts with myosin to facilitate contraction, and provides structural integrity to muscle cells. Mutations in ACTA1 can cause various muscle disorders, including nemaline myopathy and other congenital myopathies, highlighting its critical role in muscle physiology and disease. Understanding the structure, function, interactions, and clinical implications of ACTA1 provides valuable insights into its role in muscle biology and potential therapeutic targets for muscle-related diseases.
Actin alpha 1 skeletal muscle(ACTA1)
ACTA,ASMA,CFTD,CFTD1,CFTDM,CMYP2A,CMYP2B,
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con ACTA1 - Actin alpha 1 skeletal muscle
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 50 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | ACTA1 | abx356870 | Chicken Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Chicken | Serum,Plasma,Other biological fluids | Sandwich | 31.2 ng/ml - 2000 ng/ml | 18.8 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | ACTA1 | abx518006 | Cow Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.312 ng/ml - 20 ng/ml | 687.5 | 96 tests | P68138 | RUO | ||
Abbexa | ACTA1 | abx051174 | Human Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 µmol/ml - 10 µmol/ml | 537.5 | 96 tests | P68133 | RUO | |
Abbexa | ACTA1 | abx195043 | Human Actin, Alpha Skeletal Muscle (ACTA1) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 62.5 pg/ml - 4000 pg/ml | 37.5 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | ACTA1 | abx351539 | Human Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | 0.94 ng/ml | 556.25 | 96 tests | P68133 | RUO |
Abbexa | ACTA1 | abx492929 | Actin, Alpha Skeletal Muscle (ACTA1) CLIA Kit | Human | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.57 ng/ml | 812.5 | 96 tests | P68133, P68134, P68136 | RUO |
Abbexa | ACTA1 | abx156759 | Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.6 ng/ml | 675 | 96 tests | P68133, P68134, P68136 | RUO |
Abbexa | ACTA1 | abx518009 | Mouse Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 537.5 | 96 tests | P68134 | RUO | |
Abbexa | ACTA1 | abx360932 | Pig Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Pig | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | ACTA1 | abx363346 | Rabbit Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Rabbit | Serum,Plasma,Other biological fluids | Sandwich | 31.2 ng/ml - 2000 ng/ml | 18.8 ng/ml | 662.5 | 96 tests | RUO | |
Abbexa | ACTA1 | abx355233 | Rabbit Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Rabbit | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.625 ng/ml - 40 ng/ml | 0.38 ng/ml | 662.5 | 96 tests | P68135 | RUO |
Abbexa | ACTA1 | abx571081 | Rat Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 0.47 ng/ml | 587.5 | 96 tests | RUO | |
Abbexa | ACTA1 | abx354231 | Rat Actin, Alpha Skeletal Muscle (ACTA1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 3.125 ng/ml - 200 ng/ml | 1.88 ng/ml | 587.5 | 96 tests | P68136 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ACTA1 | FNab10793 | anti- ACTA1 antibody | human | polyclonal | Rabbit | actin, alpha 1, skeletal muscle | IgG | Unconjugated | ELISA, WB, IHC, IF | 100µg | P68133 | RUO | |
FineTest | ACTA1 | FNab00115 | anti- ACTA1-Specific antibody | human | polyclonal | Rabbit | actin, alpha 1, skeletal muscle | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P68133 | RUO | |
Abbexa | ACTA1 | abx147942 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx109485 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA | 162.5 | 20 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx109484 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx242958 | Actin (ACTA1) Antibody | Human | Monoclonal | Rabbit | Actin (ACTA1) | Unconjugated | ELISA, WB, IHC, IF/ICC, FCM | 287.5 | 50 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx025341 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Monoclonal | Mouse | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx402232 | Actin, alpha skeletal muscle (ACTA1) Antibody | Human | Monoclonal | Rabbit | Actin, alpha skeletal muscle (ACTA1) | Unconjugated | ELISA, IHC, FCM | 287.5 | 50 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx107869 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (HRP) | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | HRP | ELISA | 162.5 | 20 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx137526 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Monoclonal | Mouse | Actin, Alpha Skeletal Muscle (ACTA1) | 225 | 5 µg | RUO | ||||
Abbexa | ACTA1 | abx106504 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (FITC) | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | FITC | 162.5 | 20 µg | P68133 | RUO | ||
Abbexa | ACTA1 | abx105087 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Biotin | ELISA | 162.5 | 20 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx230320 | Alpha Actin (ACTA) Antibody | Human | Polyclonal | Rabbit | Alpha Actin (ACTA) | Unconjugated | ELISA, WB, IP | 350 | 100 µg | P68032 | RUO | |
Abbexa | ACTA1 | abx230321 | Alpha Actin (ACTA) Antibody | Human | Polyclonal | Rabbit | Alpha Actin (ACTA) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 350 | 100 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx230319 | Alpha Actin (ACTA) Antibody | Human | Polyclonal | Rabbit | Alpha Actin (ACTA) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P68032 | RUO | |
Abbexa | ACTA1 | abx159305 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Monoclonal | Mouse | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IP | 187.5 | 50 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx230115 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx327483 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx159306 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Monoclonal | Mouse | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IP | 362.5 | 100 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx214240 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB | 250 | 50 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx242048 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx109483 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC | 162.5 | 20 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx110769 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P68133 | RUO | |
Abbexa | ACTA1 | abx119042 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | WB, IHC | 43.75 | 10 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx340118 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACTA1 | abx326944 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | WB | 187.5 | 50 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx328683 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Human | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P68133 | RUO | |
Abbexa | ACTA1 | abx108758 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (HRP) | Mouse | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | HRP | ELISA | 162.5 | 20 µg | P68134 | RUO | |
Abbexa | ACTA1 | abx105922 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (Biotin) | Mouse | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Biotin | ELISA | 162.5 | 20 µg | P68134 | RUO | |
Abbexa | ACTA1 | abx107337 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody (FITC) | Mouse | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | FITC | 162.5 | 20 µg | P68134 | RUO | ||
Abbexa | ACTA1 | abx110214 | Actin, Alpha Skeletal Muscle (ACTA1) Antibody | Mouse | Polyclonal | Rabbit | Actin, Alpha Skeletal Muscle (ACTA1) | Unconjugated | ELISA, WB | 162.5 | 20 µg | P68134 | RUO | |
Abbexa | ACTA1 | abx319954 | Actin Alpha 1B, Skeletal Muscle (ACTA1B) Antibody | Zebrafish | Polyclonal | Rabbit | Actin Alpha 1B, Skeletal Muscle (ACTA1B) | Unconjugated | ELISA, WB | 162.5 | 20 µg | Q6XNL8 | RUO | |
Abbexa | ACTA1 | abx319993 | Actin Alpha 1B, Skeletal Muscle (ACTA1B) Antibody (Biotin) | Zebrafish | Polyclonal | Rabbit | Actin Alpha 1B, Skeletal Muscle (ACTA1B) | Biotin | ELISA | 162.5 | 20 µg | Q6XNL8 | RUO | |
Abbexa | ACTA1 | abx319992 | Actin Alpha 1B, Skeletal Muscle (ACTA1B) Antibody (FITC) | Zebrafish | Polyclonal | Rabbit | Actin Alpha 1B, Skeletal Muscle (ACTA1B) | FITC | 162.5 | 20 µg | Q6XNL8 | RUO | ||
Abbexa | ACTA1 | abx319991 | Actin Alpha 1B, Skeletal Muscle (ACTA1B) Antibody (HRP) | Zebrafish | Polyclonal | Rabbit | Actin Alpha 1B, Skeletal Muscle (ACTA1B) | HRP | ELISA | 162.5 | 20 µg | Q6XNL8 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACTA1 | abx652372 | Actin, Alpha Skeletal Muscle (ACTA1) Protein | Human, Mouse, Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 337.5 | 50 µg | P68133, P68134, P68136 | RUO |
FineTest | ACTA1 | P0556 | Recombinant Human ACTA1 | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P68133 | RUO |
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