Actin, Alpha Skeletal Muscle (ACTA1) CLIA Kit
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935106861
info@markelab.com
Precio
845€ (96 tests)
CLIA Kits ACTA1
proveedor
Abbexareference
abx492929Tested Applications
CLIAreactivity
Human, Mouse, Ratstatus
RUOclonality
Descripción
ACTA1 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Background
ACTA1 encodes for actin alpha 1, a protein that is a key component of the thin filaments in skeletal muscle. ACTA1 is a protein that plays a crucial role in muscle formation and function. Its expression is induced by various stimuli and conditions that promote muscle development. In response to these stimuli, committed cells such as satellite cells undergo fusion to form myotubes, which eventually mature into muscle fibers. The expression of skeletal alpha actin is not only a hallmark of muscle formation but also serves as a trigger for the expression of other "myogenic genes." These genes are essential for the intricate process of muscle development and include factors involved in myoblast differentiation, fusion, and maturation. Therefore, the expression of ACTA1 is pivotal in orchestrating the molecular events necessary for the formation and maintenance of skeletal muscle tissue. The regulation of ACTA1 expression is tightly controlled and is influenced by various signaling pathways and transcription factors involved in muscle development and regeneration. Dysregulation of ACTA1 expression or mutations in the ACTA1 gene can lead to muscle disorders and myopathies, highlighting the critical role of skeletal alpha actin in muscle biology and physiology.
Características del producto
category
CLIA Kits
immunogen target
Actin, Alpha Skeletal Muscle (ACTA1)
reactivity
Human, Mouse, Rat
test range
1.56 ng/ml - 100 ng/ml
sensitivity
< 0.57 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ACTA,ASMA,CFTD,CFTD1,CFTDM,CMYP2A,CMYP2B
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACTA1
dry ice
No
uniprot id
gene id
note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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