Actin, Alpha Skeletal Muscle (ACTA1) Antibody

Este producto es parte de ACTA1 - Actin alpha 1 skeletal muscle
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260€ (50 µl)

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935106861
info@markelab.com
name
Actin, Alpha Skeletal Muscle (ACTA1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx214240
tested applications
ELISA, WB

Description

ACTA1 Antibody is a Rabbit Polyclonal against ACTA1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Actin, Alpha Skeletal Muscle (ACTA1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/1000 - 1/2000, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P68133
Gene ID
58
Alias
ACTA,ASMA,CFTD,CFTD1,CFTDM,CMYP2A,CMYP2B
Background
Antibody anti-ACTA1
Status
RUO

Descripción

ACTA1 encodes for actin alpha 1, a protein that is a key component of the thin filaments in skeletal muscle. ACTA1 is a protein that plays a crucial role in muscle formation and function. Its expression is induced by various stimuli and conditions that promote muscle development. In response to these stimuli, committed cells such as satellite cells undergo fusion to form myotubes, which eventually mature into muscle fibers. The expression of skeletal alpha actin is not only a hallmark of muscle formation but also serves as a trigger for the expression of other "myogenic genes." These genes are essential for the intricate process of muscle development and include factors involved in myoblast differentiation, fusion, and maturation. Therefore, the expression of ACTA1 is pivotal in orchestrating the molecular events necessary for the formation and maintenance of skeletal muscle tissue. The regulation of ACTA1 expression is tightly controlled and is influenced by various signaling pathways and transcription factors involved in muscle development and regeneration. Dysregulation of ACTA1 expression or mutations in the ACTA1 gene can lead to muscle disorders and myopathies, highlighting the critical role of skeletal alpha actin in muscle biology and physiology.

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