Family main features
AKT3, also known as RAC-gamma serine/threonine-protein kinase, is one of the three isoforms of the AKT (Protein Kinase B) family of serine/threonine kinases. Like AKT1 and AKT2, AKT3 plays a crucial role in regulating various cellular processes, including cell survival, proliferation, growth, and metabolism. AKT3 is activated downstream of the phosphoinositide 3-kinase (PI3K) signaling pathway, which is activated by growth factors and other extracellular stimuli. Activation of AKT3 occurs through phosphorylation at key residues, including threonine 305 (Thr305) and serine 472 (Ser472). Once activated, AKT3 phosphorylates a wide range of substrates involved in diverse cellular functions. While AKT1 and AKT2 are ubiquitously expressed in many tissues, AKT3 exhibits a more restricted pattern of expression, with higher expression levels observed in the brain, heart, and skeletal muscle. This tissue-specific expression pattern suggests distinct roles for AKT3 in these tissues. AKT3 is involved in brain development and neuronal survival. Studies have shown that AKT3 plays a critical role in regulating neuronal migration, axon outgrowth, and dendritic arborization during brain development. Dysregulation of AKT3 signaling has been implicated in various neurological disorders, including autism spectrum disorders and epilepsy. AKT3 is also involved in other cellular processes such as cell proliferation, survival, and metabolism. Dysregulation of AKT3 signaling has been implicated in various diseases, including cancer, metabolic disorders, and cardiovascular diseases.
AKT3 is a crucial member of the AKT kinase family, with specific roles in brain development, cell survival, and growth. Its activation and functions are essential for normal cellular processes and brain function. Dysregulation of AKT3 is associated with various pathologies, including cancers and neurological disorders, making it an important target for therapeutic interventions. Understanding the specific roles and regulatory mechanisms of AKT3 provides valuable insights into its contribution to health and disease.
RAC-gamma serine/threonine-protein kinase (AKT3)
AKT3,PKBG,RAC-PK-gamma,STK-2
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Esta página contiene 26 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | AKT3 | EH6215 | Human AKT3(Protein kinase Akt-3) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q9Y243 | RUO | ||
Abbexa | AKT3 | abx152751 | Human RAC-Gamma Serine/Threonine Protein Kinase (AKT3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.6 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | AKT3 | abx573770 | Human RAC-Gamma Serine/Threonine Protein Kinase (AKT3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | 0.94 ng/ml | 587.5 | 96 tests | Q9Y243 | RUO |
Abbexa | AKT3 | abx352992 | Mouse RAC-Gamma Serine/Threonine Protein Kinase (AKT3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 587.5 | 96 tests | Q9WUA6 | RUO |
FineTest | AKT3 | ER1857 | Rat AKT3(RAC-gamma serine/threonine-protein kinase) ELISA Kit | rat | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 78.125-5000pg/ml | 96T | Q63484 | RUO | ||
Abbexa | AKT3 | abx353874 | Rat RAC-Gamma Serine/Threonine Protein Kinase (AKT3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | 0.94 ng/ml | 587.5 | 96 tests | Q63484 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | AKT3 | FNab00273 | anti- AKT3 antibody | human | polyclonal | Rabbit | v-akt murine thymoma viral oncogene homolog 3(protein kinase B, gamma) | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q9Y243 | RUO | |
Abbexa | AKT3 | abx033132 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx010372 | RAC-Gamma Serine/threonine-Protein Kinase (Akt3) Antibody | Human | Monoclonal | Mouse | RAC-Gamma Serine/threonine-Protein Kinase (Akt3) | Unconjugated | ELISA | 362.5 | 100 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx337411 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody (HRP) | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | HRP | ELISA | 162.5 | 20 µg | Q9Y243 | RUO | |
Abbexa | AKT3 | abx337413 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody (Biotin) | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | Biotin | ELISA | 162.5 | 20 µg | Q9Y243 | RUO | |
Abbexa | AKT3 | abx337412 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody (FITC) | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | FITC | 162.5 | 20 µg | Q9Y243 | RUO | ||
Abbexa | AKT3 | abx224430 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Monoclonal | Mouse | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, FCM | 362.5 | 100 µl | P19022 | RUO | |
Abbexa | AKT3 | abx224313 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Monoclonal | Mouse | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | ELISA, IF/ICC, FCM | 362.5 | 100 µl | P19022 | RUO | ||
Abbexa | AKT3 | abx025206 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Monoclonal | Mouse | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB, IHC | 250 | 80 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx338888 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, IP | 162.5 | 20 µg | Q9Y243 | RUO | |
Abbexa | AKT3 | abx326935 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | Unconjugated | WB | 187.5 | 50 µg | Q9Y243 | RUO | |
Abbexa | AKT3 | abx038464 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | AKT3 | abx116582 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx432305 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Goat | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | AKT3 | abx214471 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx214472 | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/Threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx033131 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | Q9Y243 | RUO | |
Abbexa | AKT3 | abx230273 | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody | Human | Polyclonal | Rabbit | RAC-Gamma Serine/threonine-Protein Kinase (AKT3) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q9Y243 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
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Abbexa | AKT3 | abx693629 | Mouse RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Protein | Mouse | Recombinant | Insect | SDS-PAGE | 775 | 50 µg | Q9WUA6-1 | RUO | |
Abbexa | AKT3 | abx693695 | Mouse RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Protein | Mouse | Recombinant | Insect | SDS-PAGE | 825 | 50 µg | Q9WUA6-1 | RUO |
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