Human AKT3 (Protein kinase Akt-3) QuickTest ELISA Kit

Este producto es parte de AKT3 - RAC-gamma serine/threonine-protein kinase 3
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935106861
info@markelab.com
name
Human AKT3 (Protein kinase Akt-3) QuickTest ELISA Kit
category
ELISA Kits
provider
FineTest
reference
QT-EH6215
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Assay Data
120 minutes
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9Y243
Alias
AKT3,PKBG,RAC-PK-gamma,STK-2
Background
Elisa kits for AKT3
Status
RUO

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AKT3 is one of 3 closely related serine/threonine-protein kinases(AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.

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