Family main features
NR4A1, also known as Nur77, NGFI-B, and TR3, is a member of the nuclear receptor subfamily 4 group A. It is an immediate-early response gene that plays a crucial role in the regulation of various physiological processes, including metabolism, inflammation, apoptosis, and cell proliferation. NR4A1 is an orphan nuclear receptor, meaning its endogenous ligand is not well-defined. It is rapidly induced by diverse stimuli, such as growth factors, stress signals, and inflammatory cytokines. NR4A1 is implicated in the development and function of several tissues, including the nervous system, immune system, and cardiovascular system, making it a critical regulator of homeostasis and disease.
NR4A1 possesses a typical nuclear receptor structure comprising:
NR4A1 belongs to the NR4A family of nuclear receptors, which includes:
These receptors share structural similarities and often have overlapping functions but can also regulate distinct sets of genes.
NR4A1 (Nur77) is an orphan nuclear receptor with a crucial role in regulating apoptosis, metabolism, inflammation, and cell proliferation. It has a typical nuclear receptor structure with an NTD, DBD, hinge region, and LBD. NR4A1 functions through binding specific DNA elements and modulating gene expression. Its diverse roles in physiological processes and diseases, including cancer, cardiovascular diseases, metabolic disorders, and neurodegenerative diseases, make it a significant target for therapeutic interventions. Understanding the detailed mechanisms of NR4A1's action and its regulation could lead to novel treatments for these conditions.
nuclear receptor subfamily 4 group A member 1 (NR4A1)
HMR,N10,TR3,NP10,GFRP1,NAK-1,NGFIB,NUR77,Early response protein NAK1,Orphan nuclear receptor HMR,Testicular receptor 3
nuclear receptor subfamily 4 group A member 2 (NR4A2)
NOT,RNR1,HZF-3,IDLDP,NURR1,TINUR,Immediate-early response protein NOT,Orphan nuclear receptor NURR1
nuclear receptor subfamily 4 group A member 3 (NR4A3)
CHN,CSMF,NOR1,MINOR,Nuclear hormone receptor NOR-1,Neuron-derived orphan receptor 1,Mitogen-induced nuclear orphan receptor
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con NR4A1 - nuclear receptor subfamily 4 group A member
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 27 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NR4A2 | abx555780 | Cow Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q08E53 | RUO | ||
Abbexa | NR4A1 | abx259742 | Human Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | P22736 | RUO |
Abbexa | NR4A2 | abx555398 | Human Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | P43354 | RUO | |
Abbexa | NR4A2 | abx494459 | Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.118 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | NR4A2 | abx258022 | Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | NR4A3 | abx535829 | Human Nuclear receptor subfamily 4 group A member 3 (NR4A3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q92570 | RUO | ||
Abbexa | NR4A1 | abx535827 | Mouse Nuclear receptor subfamily 4 group A member 1 (NR4A1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P12813 | RUO | ||
Abbexa | NR4A2 | abx555621 | Mouse Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.035 ng/ml | 687.5 | 96 tests | Q06219 | RUO |
Abbexa | NR4A2 | abx555715 | Rat Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 31.2 pg/ml - 2000 pg/ml | < 7.5 pg/ml | 687.5 | 96 tests | Q07917 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NR4A1 | abx320622 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, IHC | 237.5 | 50 µl | P22736 | RUO | |
Abbexa | NR4A1 | abx114198 | Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P22736 | RUO | |
Abbexa | NR4A1 | abx235935 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, WB | 350 | 100 µg | P22736 | RUO | |
Abbexa | NR4A1 | abx326598 | Nuclear Receptor Subfamily 4 Group A Member 1 Phospho-Ser351 (NR4A1 pS351) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 Phospho-Ser351 (NR4A1 pS351) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P22736 | RUO | |
Abbexa | NR4A1 | abx032784 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, WB | 281.25 | 80 µl | P22736 | RUO | |
Abbexa | NR4A1 | abx012842 | Nuclear Receptor NR4A1 Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor NR4A1 | Unconjugated | WB, IHC | 43.75 | 10 µg | P22736 | RUO | |
Abbexa | NR4A1 | abx037806 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | NR4A1 | abx214293 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, WB | 250 | 50 µl | P22736 | RUO | |
Abbexa | NR4A1 | abx329921 | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P22736 | RUO | |
Abbexa | NR4A2 | abx235936 | Intermediate-Early Receptor Protein (NR4A2) Antibody | Human | Polyclonal | Rabbit | Intermediate-Early Receptor Protein (NR4A2) | Unconjugated | ELISA, IHC | 350 | 100 µg | P43354 | RUO | |
Abbexa | NR4A2 | abx376077 | Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) | Unconjugated | ELISA, WB | 337.5 | 100 µg | P43354 | RUO | |
Abbexa | NR4A2 | abx114199 | Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) | Unconjugated | ELISA, IHC | 612.5 | 100 µl | P43354 | RUO | |
Abbexa | NR4A2 | abx241582 | Nuclear receptor subfamily 4 group A member 2 (NR4A2) Antibody | Human | Polyclonal | Rabbit | Nuclear receptor subfamily 4 group A member 2 (NR4A2) | Unconjugated | ELISA, IHC | 250 | 50 µl | P43354 | RUO | |
Abbexa | NR4A2 | abx213782 | Nuclear receptor subfamily 4 group A member 2 (NR4A2) Antibody | Human | Polyclonal | Rabbit | Nuclear receptor subfamily 4 group A member 2 (NR4A2) | Unconjugated | ELISA, IHC | 250 | 50 µl | P43354 | RUO | |
Abbexa | NR4A3 | abx122520 | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) | Unconjugated | ELISA, IHC | 337.5 | 100 µg | Q92570 | RUO | |
Abbexa | NR4A3 | abx028553 | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q92570 | RUO | |
Abbexa | NR4A3 | abx327866 | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q92570 | RUO | |
Abbexa | NR4A3 | abx014689 | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) Antibody | Human | Polyclonal | Rabbit | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q92570 | RUO |
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