Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) Antibody
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Description
Rabbit Polyclonal against the NR4A3 protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92570 |
| Alias | CHN,CSMF,NOR1,MINOR,Nuclear hormone receptor NOR-1,Neuron-derived orphan receptor 1,Mitogen-induced nuclear orphan receptor |
| Background | Antibody anti-NR4A3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Nuclear receptor subfamily 4 group A member 3 (NR4A3), also known as NOR1, is a nuclear receptor that regulates gene expression in response to various extracellular signals, including growth factors, stress hormones, and cytokines NR4A3 is involved in controlling cell proliferation, apoptosis, and differentiation, particularly in immune cells and tissues related to metabolism It plays a role in regulating inflammation and immune responses by modulating the expression of pro-inflammatory genes, thus influencing conditions such as atherosclerosis, diabetes, and autoimmune diseases NR4A3 also has functions in metabolic processes, including the regulation of lipid metabolism and insulin sensitivity, and is involved in the response to oxidative stress and cellular damage Dysregulation of NR4A3 has been linked to various pathological conditions, including cardiovascular diseases, cancer, and chronic inflammatory diseases It also plays a role in regulating the circadian rhythm and metabolic health, highlighting its potential as a target for therapeutic strategies aimed at treating metabolic and immune-related disorders
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