Family main features
Neuronal Cell Adhesion Molecule (NRCAM) is a member of the L1 family of cell adhesion molecules (CAMs), which play a crucial role in the development and function of the nervous system. NRCAM is encoded by the NRCAM gene located on chromosome 7q31. It is predominantly expressed in the nervous system but also found in other tissues. NRCAM mediates cell-cell interactions through homophilic (NRCAM to NRCAM) and heterophilic (NRCAM to other molecules) binding, facilitating processes such as axon guidance, synaptic formation, and maintenance, as well as cellular migration. It is integral to the formation of neural circuits and the establishment of functional connectivity within the brain.
NRCAM is a transmembrane glycoprotein with a multi-domain structure, essential for its function in cell adhesion and signaling:
NRCAM belongs to the L1 family of cell adhesion molecules, which includes other members such as L1CAM, CHL1, and neurofascin. These molecules share structural similarities and functional overlaps but have distinct roles in neural development and function.
NRCAM plays a variety of roles in the nervous system and beyond:
Alterations in NRCAM expression and function are associated with various neurological and psychiatric disorders:
NRCAM is a multifunctional cell adhesion molecule critical for the proper development and functioning of the nervous system. Its structure, characterized by Ig and FnIII domains, allows it to mediate cell-cell interactions and signal transduction, influencing axon guidance, synaptic formation, and cell migration. The dysregulation of NRCAM is associated with several neurodevelopmental, psychiatric, and neurological disorders, as well as certain cancers. Understanding the molecular mechanisms underlying NRCAM's functions and its role in disease can provide insights into potential therapeutic strategies for these conditions.
neuronal cell adhesion molecule (NRCAM)
NEDNMS,NgCAM-related cell adhesion molecule,Nr-CAM,Neuronal surface protein Bravo
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con NRCAM - neuronal cell adhesion molecule
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 24 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | NRCAM | abx381881 | Human Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.054 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | NRCAM | abx390024 | Mouse Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | Q810U4 | RUO |
Abbexa | NRCAM | abx391692 | Rat Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 46.9 pg/ml | 687.5 | 96 tests | P97686 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | NRCAM | FNab05852 | anti- NRCAM antibody | human | polyclonal | Rabbit | neuronal cell adhesion molecule | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q92823 | RUO | |
Abbexa | NRCAM | abx122663 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | NRCAM | abx334203 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | Q92823 | RUO | |
Abbexa | NRCAM | abx015947 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, IF/ICC | 362.5 | 100 µl | Q92823 | RUO | |
Abbexa | NRCAM | abx336779 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody (FITC) | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | FITC | 162.5 | 20 µg | Q92823 | RUO | ||
Abbexa | NRCAM | abx336780 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody (Biotin) | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Biotin | ELISA | 162.5 | 20 µg | Q92823 | RUO | |
Abbexa | NRCAM | abx336778 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody (HRP) | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | HRP | ELISA | 162.5 | 20 µg | Q92823 | RUO | |
Abbexa | NRCAM | abx443309 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (FITC) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | FITC | WB, IF/ICC | 600 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx235852 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q92823 | RUO | |
Abbexa | NRCAM | abx114080 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q92823 | RUO | |
Abbexa | NRCAM | abx440220 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (ATTO390) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | ATTO390 | WB, IF/ICC | 612.5 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx440501 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (ATTO488) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | ATTO488 | WB, IF/ICC | 612.5 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx444433 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (PE) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | PE | WB, IF/ICC | 600 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx376082 | Neuronal Cell Adhesion Molecule (NRCAM) Antibody | Human | Polyclonal | Rabbit | Neuronal Cell Adhesion Molecule (NRCAM) | Unconjugated | ELISA, WB | 337.5 | 100 µg | Q92823 | RUO | |
Abbexa | NRCAM | abx444152 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (PerCP) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | PerCP | WB, IF/ICC | 612.5 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx441063 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (ATTO594) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | ATTO594 | WB, IF/ICC | 612.5 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx443590 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (HRP) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | HRP | WB, IF/ICC | 600 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx445071 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | Unconjugated | WB, IF/ICC | 550 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx442749 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (APC) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | APC | WB, IF/ICC | 612.5 | 100 µg | Q810U4 | RUO | |
Abbexa | NRCAM | abx443029 | Neuronal Cell Adhesion Molecule (NrCAM) Antibody (Biotin) | Human | Monoclonal | Mouse | Neuronal Cell Adhesion Molecule (NrCAM) | Biotin | WB, IF/ICC | 600 | 100 µg | Q810U4 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NRCAM | abx650867 | Human NRCAM Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 175 | 10 µg | Q92823 | RUO |
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