Neuronal Cell Adhesion Molecule (NrCAM) Antibody (ATTO488)
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Description
NrCAM Antibody is a Mouse Monoclonal against NrCAM.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuronal Cell Adhesion Molecule (NrCAM) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/1000, IF/ICC: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | ATTO488 |
| Isotype | IgG2a |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.1% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q810U4 |
| Gene ID | 319504 |
| NCBI Accession | NP_001139503.1 |
| Alias | NEDNMS,NgCAM-related cell adhesion molecule,Nr-CAM,Neuronal surface protein Bravo |
| Background | Antibody anti-NRCAM |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Neuronal Cell Adhesion Molecule (NRCAM) is a member of the L1 family of cell adhesion molecules (CAMs), which play a crucial role in the development and function of the nervous system. NRCAM is encoded by the NRCAM gene located on chromosome 7q31. It is predominantly expressed in the nervous system but also found in other tissues. NRCAM mediates cell-cell interactions through homophilic (NRCAM to NRCAM) and heterophilic (NRCAM to other molecules) binding, facilitating processes such as axon guidance, synaptic formation, and maintenance, as well as cellular migration. It is integral to the formation of neural circuits and the establishment of functional connectivity within the brain.
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