Rat Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit

Este producto es parte de NRCAM - neuronal cell adhesion molecule
Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Rat Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx391692
tested applications
ELISA

Description

Rat Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat NRCAM concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

CategoryELISA Kits
Immunogen TargetNeuronal Cell Adhesion Molecule (NRCAM)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range78 pg/ml - 5000 pg/ml
Sensitivity< 46.9 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma, tissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDP97686
AliasNEDNMS,NgCAM-related cell adhesion molecule,Nr-CAM,Neuronal surface protein Bravo
BackgroundElisa kits for NRCAM
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Neuronal Cell Adhesion Molecule (NRCAM) is a member of the L1 family of cell adhesion molecules (CAMs), which play a crucial role in the development and function of the nervous system. NRCAM is encoded by the NRCAM gene located on chromosome 7q31. It is predominantly expressed in the nervous system but also found in other tissues. NRCAM mediates cell-cell interactions through homophilic (NRCAM to NRCAM) and heterophilic (NRCAM to other molecules) binding, facilitating processes such as axon guidance, synaptic formation, and maintenance, as well as cellular migration. It is integral to the formation of neural circuits and the establishment of functional connectivity within the brain.

Related Products

FNab05852

anti- NRCAM antibody

Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

Ver Producto
abx015947

Neuronal Cell Adhesion Molecule (NRCAM) Antibody

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily.This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains.This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth.This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration.Allelic variants of this gene have been associated with autism and addiction vulnerability.Alternative splicing results in multiple transcript variants encoding different isoforms.

Ver Producto
abx114080

Neuronal Cell Adhesion Molecule (NRCAM) Antibody

Neuronal Cell Adhesion Molecule Antibody is a Rabbit Polyclonal antibody against Neuronal Cell Adhesion Molecule.

Ver Producto