Neuronal Cell Adhesion Molecule (NrCAM) Antibody (APC)
637€ (100 µg)
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Name
Neuronal Cell Adhesion Molecule (NrCAM) Antibody (APC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx442749
Tested Applications
WB, IF/ICC
Description
NrCAM Antibody is a Mouse Monoclonal against NrCAM.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Neuronal Cell Adhesion Molecule (NrCAM) Immunogen: Fusion protein amino acids 30-845 (extracellular domain) of mouse NrCAM. Rat: 96% identity (795/822 amino acids identical). Human: 91% identity (753/822 amino acids identical) ~50% identity with Neurofascin.. |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Laser Line: 647 Excitation/Emission: 651/660 |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/1000, IF/ICC: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2a |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.1% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at 4°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q810U4 |
| Gene ID | 319504 |
| NCBI Accession | NP_001139503.1 |
| Alias | NEDNMS,NgCAM-related cell adhesion molecule,Nr-CAM,Neuronal surface protein Bravo |
| Background | Antibody anti-NRCAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Neuronal Cell Adhesion Molecule (NRCAM) is a member of the L1 family of cell adhesion molecules (CAMs), which play a crucial role in the development and function of the nervous system. NRCAM is encoded by the NRCAM gene located on chromosome 7q31. It is predominantly expressed in the nervous system but also found in other tissues. NRCAM mediates cell-cell interactions through homophilic (NRCAM to NRCAM) and heterophilic (NRCAM to other molecules) binding, facilitating processes such as axon guidance, synaptic formation, and maintenance, as well as cellular migration. It is integral to the formation of neural circuits and the establishment of functional connectivity within the brain.
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