Family main features
MIA (Melanoma Inhibitory Activity), also known as MIA SH3 domain-containing protein is a protein that plays important roles in cell signaling, cell adhesion, and cancer progression. MIA is a small secreted protein, typically around 11 kDa in size, containing a Src homology 3 (SH3) domain. The SH3 domain is a protein interaction domain found in many signaling proteins, allowing MIA to interact with various other proteins involved in cellular processes. MIA is involved in signaling pathways that regulate cell proliferation, migration, and survival. It interacts with several intracellular signaling molecules and modulates their activity, thereby influencing cellular responses to extracellular stimuli. MIA has been implicated in the regulation of ECM remodeling, particularly in the context of cancer metastasis. It can affect the expression and activity of ECM-degrading enzymes, such as matrix metalloproteinases (MMPs), and modulate cell adhesion and invasion. MIA has been also shown to promote angiogenesis. MIA expression is often elevated in various types of cancer, including melanoma, pancreatic cancer, and colorectal cancer. High levels of MIA expression have been associated with increased metastatic potential and poor prognosis in cancer patients.
MIA is a small, secreted protein comprising approximately 108 amino acids. Its structure includes:
MIA belongs to a family of proteins that includes MIA2 and TANGO, which share structural similarities and functions related to cell migration and interaction with the extracellular matrix. These proteins can be classified based on their SH3 domain and their roles in tumor biology.
MIA plays several critical roles in biological processes, particularly related to cancer:
MIA is a small, secreted protein with a critical role in melanoma progression and metastasis. Its interactions with integrins and extracellular matrix proteins facilitate tumor cell migration and invasion. As a potential biomarker and therapeutic target, MIA holds significant promise in the diagnosis and treatment of melanoma and possibly other cancers. Further research into its precise mechanisms and broader biological functions may expand its clinical applications.
Melanoma-derived growth regulatory protein ( MIA)
Melanoma inhibitory activity protein,MIA1,CD-RAP
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con MIA - MIA SH3 domain containing
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 29 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | MIA | abx518689 | Cow Melanoma Inhibitory Activity / CD-RAP (MIA) ELISA Kit | Cow | Serum,Plasma,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q28038 | RUO | ||
FineTest | MIA | EH0227 | Human MIA(Melanoma Inhibitory Activity Protein 1) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 7.813-500pg/ml | 96T | Q16674 | RUO | ||
Abbexa | MIA | abx495499 | Human Melanoma-Derived Growth Regulatory Protein (MIA) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 7.81 pg/ml - 500 pg/ml | < 3.1 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | MIA | abx197270 | Human Melanoma-Derived Growth Regulatory Protein (MIA) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 7.81 pg/ml - 500 pg/ml | 4.69 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | MIA | abx152332 | Human Melanoma-Derived Growth Regulatory Protein (MIA) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 7.81 pg/ml - 500 pg/ml | < 3.1 pg/ml | 687.5 | 96 tests | RUO | |
Abbexa | MIA | abx251618 | Human Melanoma-Derived Growth Regulatory Protein (MIA) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 7.81 pg/ml - 500 pg/ml | 4.69 pg/ml | 587.5 | 96 tests | Q16674 | RUO |
Abbexa | MIA | abx154381 | Mouse Melanoma-Derived Growth Regulatory Protein (MIA) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 37 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | MIA | abx495500 | Mouse Melanoma-Derived Growth Regulatory Protein (MIA) CLIA Kit | Mouse | Serum, plasma, tissue homogenates and other biological fluids. | Sandwich | 78.12 pg/ml - 5000 pg/ml | < 37 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | MIA | abx495501 | Rat Melanoma-Derived Growth Regulatory Protein (MIA) CLIA Kit | Rat | Serum, plasma and other biological fluids. | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.57 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MIA | abx155818 | Rat Melanoma-Derived Growth Regulatory Protein (MIA) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.57 ng/ml | 662.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | MIA | FNab05173 | anti- MIA antibody | human | polyclonal | Rabbit | melanoma inhibitory activity | IgG | Unconjugated | ELISA, IHC | 100µg | Q16674 | RUO | |
Abbexa | MIA | abx430034 | Melanoma Inhibitory Activity (MIA) Antibody | Human | Polyclonal | Goat | Melanoma Inhibitory Activity (MIA) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | MIA | abx336488 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody (Biotin) | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Biotin | ELISA | 162.5 | 20 µg | Q16674 | RUO | |
Abbexa | MIA | abx334046 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | Q16674 | RUO | |
Abbexa | MIA | abx336487 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody (FITC) | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | FITC | 162.5 | 20 µg | Q16674 | RUO | ||
Abbexa | MIA | abx323228 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | ELISA, IHC | 187.5 | 50 µg | Q16674 | RUO | |
Abbexa | MIA | abx336486 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody (HRP) | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | HRP | ELISA | 162.5 | 20 µg | Q16674 | RUO | |
Abbexa | MIA | abx235173 | Melanoma Inhibitory Activity (MIA) Antibody | Human | Polyclonal | Rabbit | Melanoma Inhibitory Activity (MIA) | Unconjugated | ELISA, IHC | 350 | 100 µg | Q16674 | RUO | |
Abbexa | MIA | abx326553 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | ELISA, IHC | 187.5 | 50 µg | Q16674 | RUO | |
Abbexa | MIA | abx014575 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Human | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | IHC | 43.75 | 10 µg | Q16674 | RUO | |
Abbexa | MIA | abx130858 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Mouse | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q61865 | RUO | |
Abbexa | MIA | abx130313 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Rat | Polyclonal | Rabbit | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | Q62946 | RUO | |
Abbexa | MIA | abx173529 | Melanoma-Derived Growth Regulatory Protein (MIA) Antibody | Rat | Monoclonal | Mouse | Melanoma-Derived Growth Regulatory Protein (MIA) | Unconjugated | WB, IHC, IF/ICC | 850 | 1 ml | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | MIA | abx167946 | Rat Melanoma-Derived Growth Regulatory Protein (MIA) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 237.5 | 10 µg | Q62946 | RUO |
Abbexa | MIA | abx650742 | Mouse Melanoma-Derived Growth Regulatory Protein (MIA) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q61865 | RUO |
Abbexa | MIA | abx261812 | Human Melanoma-Derived Growth Regulatory Protein (MIA) Protein | Human | Recombinant | Unconjugated | SDS-PAGE | 225 | 5 µg | Q16674 | RUO | |
Abbexa | MIA | abx655766 | Human Melanoma-Derived Growth Regulatory Protein (MIA) Protein (Active) | Human | Recombinant | Unconjugated | WB, SDS-PAGE | 4650 | 1 mg | RUO | ||
Abbexa | MIA | abx260772 | Human Melanoma-Derived Growth Regulatory Protein (MIA) Protein | Human | Recombinant | Unconjugated | SDS-PAGE | 225 | 5 µg | Q16674 | RUO | |
Abbexa | MIA | abx654338 | Human Melanoma-Derived Growth Regulatory Protein (MIA) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 3087.5 | 1 mg | RUO |
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