Melanoma-Derived Growth Regulatory Protein (MIA) Antibody
884€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Melanoma-Derived Growth Regulatory Protein (MIA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173529
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Melanoma-Derived Growth Regulatory Protein (MIA) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Melanoma inhibitory activity protein,MIA1,CD-RAP |
| Background | Antibody anti-MIA |
| Status | RUO |
Descripción
MIA, also known as Melanoma Inhibitory Activity, is a small secreted protein primarily expressed in melanocytes and chondrocytes, where it regulates cell adhesion, migration, and tumor progression It acts by disrupting the interaction between integrins and the extracellular matrix, facilitating detachment and migration of tumor cells MIA is highly expressed in malignant melanoma and is used as a biomarker for disease progression, metastasis, and treatment monitoring Elevated MIA levels are also observed in other cancers, such as chondrosarcoma and hepatocellular carcinoma, where it contributes to tumor invasiveness Its role extends to cartilage homeostasis and chondrocyte differentiation, implicating MIA in cartilage-related disorders like osteoarthritis Targeting MIA holds therapeutic potential in inhibiting tumor cell dissemination and cartilage degeneration
Related Products
Human MIA (Melanoma Inhibitory Activity Protein 1) ELISA Kit
Ver Producto
MIA antibody
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Ver Producto