Cow Melanoma Inhibitory Activity / CD-RAP (MIA) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for MIA
proveedor
Abbexareference
abx518689Tested Applications
ELISAreactivity
Cowstatus
RUOclonality
Descripción
Cow Melanoma Inhibitory Activity / CD-RAP (MIA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Melanoma-derived growth regulatory protein concentrations in serum, plasma and other biological fluids.
Background
MIA, also known as Melanoma Inhibitory Activity, is a small secreted protein primarily expressed in melanocytes and chondrocytes, where it regulates cell adhesion, migration, and tumor progression It acts by disrupting the interaction between integrins and the extracellular matrix, facilitating detachment and migration of tumor cells MIA is highly expressed in malignant melanoma and is used as a biomarker for disease progression, metastasis, and treatment monitoring Elevated MIA levels are also observed in other cancers, such as chondrosarcoma and hepatocellular carcinoma, where it contributes to tumor invasiveness Its role extends to cartilage homeostasis and chondrocyte differentiation, implicating MIA in cartilage-related disorders like osteoarthritis Targeting MIA holds therapeutic potential in inhibiting tumor cell dissemination and cartilage degeneration
Características del producto
category
ELISA Kits
immunogen target
Melanoma Inhibitory Activity / CD-RAP (MIA)
reactivity
Cow
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
Melanoma inhibitory activity protein,MIA1,CD-RAP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MIA
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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