Family main features
Interleukin-1 Receptor Accessory Protein-like (IL1RAPL) proteins are members of the interleukin-1 receptor (IL-1R) family and share structural similarities with the interleukin-1 receptor accessory protein (IL1RAP). These proteins are encoded by the IL1RAPL1 and IL1RAPL2 genes and are primarily expressed in the central nervous system, particularly in regions associated with cognitive functions and synaptic plasticity. IL1RAPL proteins are involved in the regulation of neuronal signaling and synapse formation. Their roles extend to modulating various intracellular signaling pathways that influence neuronal development and function. Dysregulation or mutations in IL1RAPL proteins have been linked to intellectual disabilities and neurodevelopmental disorders, highlighting their importance in brain development and cognitive processes.
IL1RAPL proteins have several key structural features:
IL1RAPL family members include:
IL1RAPL proteins play essential roles in the nervous system, particularly in:
Mutations or dysregulation of IL1RAPL proteins are linked to several neurodevelopmental disorders:
IL1RAPL (Interleukin-1 Receptor Accessory Protein-like) proteins are crucial components of the interleukin-1 receptor family, primarily expressed in the brain and involved in neurodevelopment and synaptic function. They play significant roles in synaptic formation, neuronal signaling, and cognitive processes. Dysregulation or mutations in IL1RAPL proteins, particularly IL1RAPL1, are associated with neurodevelopmental disorders such as intellectual disability, autism, and epilepsy. Understanding the structure and function of IL1RAPL proteins provides insights into their roles in brain function and their potential as therapeutic targets for related neurological conditions.
Interleukin-1 Receptor Accessory Protein-like 1 (IL1RAPL1)
IL1RAPL1,IL1R8, IL1RAPL, IL-1RAPL-1, IL-1-RAPL-1, IL1RAPL-1,OPHN4
Interleukin-1 Receptor Accessory Protein-like 2 (IL1RAPL2)
IL1RAPL2,IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con IL1RAPL - Interleukin-1 Receptor Accessory Protein-like
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Esta página contiene 28 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | IL1RAPL1 | abx385040 | Human Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q9NZN1 | RUO |
Abbexa | IL1RAPL2 | abx151937 | Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) ELISA Kit | Human | Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | IL1RAPL2 | abx190226 | Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) CLIA Kit | Human | Tissue homogenates and other biological fluids. | Sandwich | 13.7 pg/ml - 10000 pg/ml | < 5.4 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | IL1RAPL1 | abx389631 | Mouse Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | P59823 | RUO |
Abbexa | IL1RAPL2 | abx389632 | Mouse Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 46.9 pg/ml | 687.5 | 96 tests | Q9ERS6 | RUO |
Abbexa | IL1RAPL1 | abx391494 | Rat Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | P59824 | RUO |
Abbexa | IL1RAPL1 | abx528706 | Rat Interleukin-1 Receptor Accessory Protein-Like 1 (IL1RAPL1) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | IL1RAPL1 | FNab04245 | anti- IL1RAPL1 antibody | human | polyclonal | Rabbit | interleukin 1 receptor accessory protein-like 1 | IgG | Unconjugated | ELISA, WB, IHC, IF, IP | 100µg | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx336153 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody (HRP) | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | HRP | ELISA | 162.5 | 20 µg | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx336154 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody (FITC) | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | FITC | 162.5 | 20 µg | Q9NZN1 | RUO | ||
Abbexa | IL1RAPL1 | abx338516 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx224394 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody | Human | Monoclonal | Mouse | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Unconjugated | ELISA, WB, IF/ICC, FCM | 362.5 | 100 µl | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx224267 | Interleukin-1 Receptor Accessory Protein-Like 1 (IL1RAPL1) Antibody | Human | Monoclonal | Mouse | Interleukin-1 Receptor Accessory Protein-Like 1 (IL1RAPL1) | ELISA, WB | 362.5 | 100 µl | Q9NZN1 | RUO | ||
Abbexa | IL1RAPL1 | abx336155 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Biotin | ELISA | 162.5 | 20 µg | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx128112 | Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx002415 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Unconjugated | WB | 175 | 20 µl | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx113227 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Unconjugated | ELISA, WB, IF/ICC | 612.5 | 100 µl | Q9NZN1 | RUO | |
Abbexa | IL1RAPL1 | abx234245 | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 1 (IL1RAPL1) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 350 | 100 µg | Q9NZN1 | RUO | |
Abbexa | IL1RAPL2 | abx173035 | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Antibody | Human | Monoclonal | Mouse | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) | Unconjugated | WB, IHC, IF/ICC | 787.5 | 1 ml | RUO | ||
Abbexa | IL1RAPL2 | abx129125 | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q9NP60 | RUO | |
Abbexa | IL1RAPL2 | abx029184 | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9NP60 | RUO | |
Abbexa | IL1RAPL2 | abx015194 | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q9NP60 | RUO | |
Abbexa | IL1RAPL2 | abx034118 | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) | Unconjugated | WB, FCM | 250 | 80 µl | Q9NP60 | RUO | |
Abbexa | IL1RAPL2 | abx325498 | Interleukin 1 Receptor Accessory Protein Like 2 (IL1RAPL2) Antibody | Human | Polyclonal | Rabbit | Interleukin 1 Receptor Accessory Protein Like 2 (IL1RAPL2) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q9NP60 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | IL1RAPL1 | P8262 | Recombinant Human IL1RAPL1 | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | Q9NZN1 | RUO | ||
Abbexa | IL1RAPL1 | abx691177 | Mouse Interleukin-1 Receptor Accessory Protein-Like 1 (IL1RAPL1) Protein | Mouse | Recombinant | HEK293 cells | SDS-PAGE | 1112.5 | 100 µg | P59823 | RUO | |
Abbexa | IL1RAPL1 | abx166179 | Human Interleukin 1 Receptor Accessory Protein Like Protein 1 (IL1RAPL1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9NZN1 | RUO |
Abbexa | IL1RAPL2 | abx167958 | Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | RUO |
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