Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx151937
tested applications
ELISA
Description
Human Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human IL1RAPL2 concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Interleukin 1 Receptor Accessory Protein Like Protein 2 (IL1RAPL2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | IL1RAPL2,IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1 |
| Background | Elisa kits for IL1RAPL2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
IL1RAPL2 is a structurally related protein in the IL-1 receptor family that exhibits specialized functions in neuronal signaling, synaptic development, and immune regulation. It shares similarities with IL1RAP but has distinct patterns of expression, being predominantly found in developing neurons and immune cells. IL1RAPL2 interacts with downstream effectors to regulate cytokine signaling, dendritic spine formation, and synaptic plasticity, influencing neurodevelopment and immune modulation. In neurons, IL1RAPL2 promotes excitatory synapse formation and dendrite maturation, which are critical for cognitive function, neuronal communication, and brain connectivity. Dysregulation or mutations in IL1RAPL2 have been associated with neurodevelopmental disorders, including autism spectrum disorders and intellectual disabilities, where altered neuronal connectivity and synaptic function contribute to cognitive impairment and behavioral deficits. Knockdown models exhibit reduced synaptic development, defective dendritic growth, and impaired immune signaling, highlighting its importance in balancing neurodevelopment, synaptic organization, and immune responses.
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