Family main features
CYFIP (cytoplasmic FMR1-interacting protein) is a multifunctional protein that plays a crucial role in synaptic function, cytoskeleton organization, and mRNA translation regulation. It was first identified through its interaction with the Fragile X Mental Retardation Protein (FMRP), which is linked to Fragile X syndrome, the most common inherited cause of intellectual disability. CYFIP is part of the WAVE regulatory complex (WRC), which is essential for actin polymerization, cell movement, and morphology.
CYFIP is a large protein with a molecular weight of approximately 140 kDa and consists of several key domains:
The structure of CYFIP allows it to act as a bridge between signaling pathways that control cytoskeletal rearrangements and the regulation of protein synthesis.
CYFIP proteins belong to a family that includes two primary isoforms:
CYFIP proteins are integral components of the WAVE complex and play significant roles in regulating the actin cytoskeleton, synaptic function, and mRNA translation. Through their interactions with FMRP and Rac1, CYFIP proteins bridge signaling pathways that control cellular morphology and synaptic plasticity. Dysregulation of CYFIP proteins is associated with various clinical conditions, including Fragile X syndrome, cancer, and neurological disorders, highlighting their importance in both cellular and physiological processes. Understanding the structure and function of CYFIP proteins is essential for elucidating their roles in health and disease.
cytoplasmic FMR1 interacting protein 1 (CYFIP1)
SHYC,SRA1,SRA-1,P140SRA-1,Specifically Rac1-associated protein 1
cytoplasmic FMR1 interacting protein 2 (CYFIP2)
DEE65,EIEE65,PIR121,p53-inducible protein 121
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con CYFIP - cytoplasmic FMR1 interacting protein
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 17 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | CYFIP1 | abx384917 | Human Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q7L576 | RUO |
Abbexa | CYFIP2 | abx386759 | Human Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q96F07 | RUO |
Abbexa | CYFIP1 | abx389318 | Mouse Cytoplasmic FMR1 Interacting protein 1 (CYFIP1) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.061 ng/ml | 700 | 96 tests | RUO | |
Abbexa | CYFIP2 | abx389319 | Mouse Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q5SQX6 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | CYFIP2 | FNab02140 | anti- CYFIP2 antibody | human | polyclonal | Rabbit | cytoplasmic FMR1 interacting protein 2 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q96F07 | RUO | |
Abbexa | CYFIP1 | abx346703 | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) | Unconjugated | ELISA, IF/ICC | 162.5 | 20 µg | Q7L576 | RUO | |
Abbexa | CYFIP1 | abx346704 | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody (HRP) | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) | HRP | ELISA | 162.5 | 20 µg | Q7L576 | RUO | |
Abbexa | CYFIP1 | abx346706 | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) | Biotin | ELISA | 162.5 | 20 µg | Q7L576 | RUO | |
Abbexa | CYFIP1 | abx346705 | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody (FITC) | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) | FITC | 162.5 | 20 µg | Q7L576 | RUO | ||
Abbexa | CYFIP1 | abx125739 | Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) | Unconjugated | WB, IP | 175 | 20 µl | Q7L576 | RUO | |
Abbexa | CYFIP2 | abx122298 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB | 337.5 | 100 µg | RUO | ||
Abbexa | CYFIP2 | abx232140 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q96F07 | RUO | |
Abbexa | CYFIP2 | abx213071 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q96F07 | RUO | |
Abbexa | CYFIP2 | abx213302 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q96F07 | RUO | |
Abbexa | CYFIP2 | abx329799 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q96F07 | RUO | |
Abbexa | CYFIP2 | abx111947 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q96F07 | RUO | |
Abbexa | CYFIP2 | abx375322 | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody | Human | Polyclonal | Rabbit | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) | Unconjugated | ELISA, WB | 337.5 | 100 µg | Q96F07 | RUO |
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