Mouse Cytoplasmic FMR1 Interacting protein 1 (CYFIP1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
728€ (96 tests)
Elisa kits for CYFIP1
proveedor
Abbexareference
abx389318Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Cytoplasmic FMR1 Interacting protein 1 (CYFIP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Cytoplasmic FMR1 Interacting protein 1 (CYFIP1) concentrations in serum, plasma and other biological fluids.
Background
Cytoplasmic FMR1 interacting protein 1 (CYFIP1) is a key protein that interacts with the fragile X mental retardation protein (FMRP) and plays an important role in modulating actin cytoskeleton dynamics and synaptic function CYFIP1 is a component of the WAVE complex, which regulates the branching of actin filaments, a process that is essential for cellular movement and the formation of protrusions such as lamellipodia and filopodia In neurons, CYFIP1 is crucial for dendritic spine formation, synaptic plasticity, and the maintenance of synaptic strength, which are vital for processes like learning, memory, and neural network development Disruption in CYFIP1 expression or function is implicated in neurodevelopmental disorders, including fragile X syndrome, where defects in synaptic function and neuronal communication contribute to cognitive deficits, developmental delays, and social impairments CYFIP1 has also been associated with cancer, as alterations in its regulation can influence cell motility, invasion, and metastasis Through its role in both the nervous system and cancer progression, CYFIP1 represents a potential target for therapies designed to treat neurological disorders and limit the spread of cancer by controlling cellular movement and actin dynamics
Características del producto
category
ELISA Kits
immunogen target
Cytoplasmic FMR1 Interacting protein 1 (CYFIP1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.061 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
SHYC,SRA1,SRA-1,P140SRA-1,Specifically Rac1-associated protein 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CYFIP1
dry ice
No
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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