Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody
637€ (100 µl)
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935106861
info@markelab.com
name
Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111947
tested applications
ELISA, WB
Description
Cytoplasmic Fmr1 Interacting Protein 2 Antibody is a Rabbit Polyclonal antibody against Cytoplasmic Fmr1 Interacting Protein 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96F07 |
| Gene ID | 26999 |
| NCBI Accession | NP_001032410.1, NM_001037333.2, NP_001278650.1, NM_001291721.1, NP_001278651.1, NM_001291722.1 |
| OMIM | 606323 |
| Alias | DEE65,EIEE65,PIR121,p53-inducible protein 121 |
| Background | Antibody anti-CYFIP2 |
| Status | RUO |
Descripción
Cytoplasmic FMR1 interacting protein 2 (CYFIP2) is a protein that interacts with the fragile X mental retardation protein (FMRP) and plays a critical role in regulating the actin cytoskeleton in neurons CYFIP2 is a key component of the WAVE complex, which controls the polymerization of actin filaments and is essential for cellular processes like migration, adhesion, and synaptic plasticity In the nervous system, CYFIP2 helps control the formation and maintenance of dendritic spines, which are critical for synaptic strength and plasticity These functions are vital for learning, memory, and the development of neural networks Disruption of CYFIP2 activity has been linked to neurological disorders, particularly fragile X syndrome, where impairments in synaptic function contribute to cognitive and behavioral deficits CYFIP2’s involvement in both synaptic plasticity and the regulation of the cytoskeleton makes it a critical player in neurodevelopment and a potential target for therapies aimed at treating neurodevelopmental disorders
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