Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody

Este producto es parte de CYFIP - cytoplasmic FMR1 interacting protein
Product Graph
637€ (100 µl)

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935106861
info@markelab.com
name
Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111947
tested applications
ELISA, WB

Description

Cytoplasmic Fmr1 Interacting Protein 2 Antibody is a Rabbit Polyclonal antibody against Cytoplasmic Fmr1 Interacting Protein 2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Cytoplasmic FMR1-Interacting Protein 2 (CYFIP2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96F07
Gene ID
26999
NCBI Accession
NP_001032410.1, NM_001037333.2, NP_001278650.1, NM_001291721.1, NP_001278651.1, NM_001291722.1
OMIM
606323
Alias
DEE65,EIEE65,PIR121,p53-inducible protein 121
Background
Antibody anti-CYFIP2
Status
RUO

Descripción

Cytoplasmic FMR1 interacting protein 2 (CYFIP2) is a protein that interacts with the fragile X mental retardation protein (FMRP) and plays a critical role in regulating the actin cytoskeleton in neurons CYFIP2 is a key component of the WAVE complex, which controls the polymerization of actin filaments and is essential for cellular processes like migration, adhesion, and synaptic plasticity In the nervous system, CYFIP2 helps control the formation and maintenance of dendritic spines, which are critical for synaptic strength and plasticity These functions are vital for learning, memory, and the development of neural networks Disruption of CYFIP2 activity has been linked to neurological disorders, particularly fragile X syndrome, where impairments in synaptic function contribute to cognitive and behavioral deficits CYFIP2’s involvement in both synaptic plasticity and the regulation of the cytoskeleton makes it a critical player in neurodevelopment and a potential target for therapies aimed at treating neurodevelopmental disorders
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