Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx346703
tested applications
ELISA, IF/ICC
Description
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) Antibody is a Rabbit Polyclonal antibody for the detection of Human CYFIP1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytoplasmic FMR1-interacting protein 1 (CYFIP1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7L576 |
| Gene ID | 23191 |
| Alias | SHYC,SRA1,SRA-1,P140SRA-1,Specifically Rac1-associated protein 1 |
| Background | Antibody anti-CYFIP1 |
| Status | RUO |
Descripción
Cytoplasmic FMR1 interacting protein 1 (CYFIP1) is a key protein that interacts with the fragile X mental retardation protein (FMRP) and plays an important role in modulating actin cytoskeleton dynamics and synaptic function CYFIP1 is a component of the WAVE complex, which regulates the branching of actin filaments, a process that is essential for cellular movement and the formation of protrusions such as lamellipodia and filopodia In neurons, CYFIP1 is crucial for dendritic spine formation, synaptic plasticity, and the maintenance of synaptic strength, which are vital for processes like learning, memory, and neural network development Disruption in CYFIP1 expression or function is implicated in neurodevelopmental disorders, including fragile X syndrome, where defects in synaptic function and neuronal communication contribute to cognitive deficits, developmental delays, and social impairments CYFIP1 has also been associated with cancer, as alterations in its regulation can influence cell motility, invasion, and metastasis Through its role in both the nervous system and cancer progression, CYFIP1 represents a potential target for therapies designed to treat neurological disorders and limit the spread of cancer by controlling cellular movement and actin dynamics
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