anti- CYFIP2 antibody

Este producto es parte de CYFIP - cytoplasmic FMR1 interacting protein
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935106861
info@markelab.com
name
anti- CYFIP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02140
tested applications
ELISA, WB, IHC

Description

Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA.

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
Primary Antibodies
Immunogen Target
cytoplasmic FMR1 interacting protein 2
Host
Rabbit
Reactivity
human,mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
130 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q96F07
Gene ID
26999
Alias
DEE65,EIEE65,PIR121,p53-inducible protein 121
Background
Antibody anti-CYFIP2
Status
RUO
Note
This product is for research use only.

Descripción

Cytoplasmic FMR1 interacting protein 2 (CYFIP2) is a protein that interacts with the fragile X mental retardation protein (FMRP) and plays a critical role in regulating the actin cytoskeleton in neurons CYFIP2 is a key component of the WAVE complex, which controls the polymerization of actin filaments and is essential for cellular processes like migration, adhesion, and synaptic plasticity In the nervous system, CYFIP2 helps control the formation and maintenance of dendritic spines, which are critical for synaptic strength and plasticity These functions are vital for learning, memory, and the development of neural networks Disruption of CYFIP2 activity has been linked to neurological disorders, particularly fragile X syndrome, where impairments in synaptic function contribute to cognitive and behavioral deficits CYFIP2’s involvement in both synaptic plasticity and the regulation of the cytoskeleton makes it a critical player in neurodevelopment and a potential target for therapies aimed at treating neurodevelopmental disorders

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