Family main features
BCL2 interacting protein 3 (BNIP3) is a pro-apoptotic member of the BCL-2 protein family, distinct in its ability to induce cell death through mechanisms that are both dependent and independent of the mitochondrial permeability transition pore. BNIP3 is encoded by the BNIP3 gene, located on chromosome 22q12. It plays a significant role in cellular response to hypoxia, stress, and various forms of cellular damage, contributing to the regulation of mitochondrial integrity and cell survival.
BNIP3 belongs to the BH3-only subgroup of the BCL-2 family, which includes other proteins like BIM, PUMA, and BAD. This subgroup is characterized by their exclusive presence of the BH3 domain, enabling them to interact with and inhibit the function of anti-apoptotic BCL-2 family members. BNIP3 is particularly noted for its role in mitochondrial dysfunction and autophagy.
BCL2 interacting protein 3 (BNIP3) is a key regulator of apoptosis and mitochondrial function, prominently featured in the BH3-only subgroup of the BCL-2 family. It facilitates mitochondrial membrane permeabilization and caspase activation through its interactions with anti-apoptotic BCL-2 proteins. Induced by hypoxic stress, BNIP3 not only promotes apoptosis but also influences mitochondrial dynamics and autophagy. Its dysregulation is associated with various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions, highlighting its potential as a therapeutic target for enhancing cell death in tumors and protecting against cell loss in degenerative diseases.
BCL2 interacting protein 3 (BNIP3)
NIP3,HABON,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
BCL2 interacting protein 3 like (BNIP3L)
BNIP3L,BNIP3A,BNIP3H,NIX,Adenovirus E1B19K-binding protein B5,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con BNIP3 - BCL2 interacting protein 3 (Like)
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 32 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | BNIP3 | abx555807 | Cow BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q32KN2 | RUO | ||
FineTest | BNIP3 | EH4053 | Human BNIP3(BCL2/adenovirus E1B 19 kDa protein-interacting protein 3) ELISA Kit | human | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.469-30ng/ml | 96T | Q12983 | RUO | ||
FineTest | BNIP3L | EH6731 | Human BNIP3L(BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | O60238 | RUO | ||
Abbexa | BNIP3 | abx257963 | Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | Q12983 | RUO |
Abbexa | BNIP3L | abx386064 | Human BCL2/adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like (BNIP3L) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.14 ng/ml | 687.5 | 96 tests | RUO | |
FineTest | BNIP3 | EM6245 | Mouse Bnip3(BCL2/adenovirus E1B 19 kDa protein-interacting protein 3) ELISA Kit | mouse | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 78.125-5000pg/ml | 96T | O55003 | RUO | ||
Abbexa | BNIP3 | abx555428 | Mouse BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | O55003 | RUO | ||
Abbexa | BNIP3L | abx503899 | Mouse BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9Z2F7 | RUO | |
Abbexa | BNIP3 | abx190756 | Rat Bcl2/Adenovirus E1B 19 kDa Interacting Protein 3 (BNIP3) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 54.9 pg/ml - 40000 pg/ml | < 22.7 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | BNIP3 | abx155269 | Rat Bcl2/Adenovirus E1B 19 kDa Interacting Protein 3 (BNIP3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.625 ng/ml - 40 ng/ml | < 0.23 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | BNIP3L | FNab00929 | anti- BNIP3L antibody | human | polyclonal | Rabbit | BCL2/adenovirus E1B 19kDa interacting protein 3-like | IgG | Unconjugated | ELISA, WB, IHC | 100µg | O60238 | RUO | |
Abbexa | BNIP3 | abx323623 | BCL2 Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2 Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q12983 | RUO | |
Abbexa | BNIP3 | abx224317 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Antibody | Human | Monoclonal | Mouse | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) | ELISA, IHC, IF/ICC, FCM | 362.5 | 100 µl | Q12983 | RUO | ||
Abbexa | BNIP3 | abx224435 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Antibody | Human | Monoclonal | Mouse | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, IF/ICC, FCM | 362.5 | 100 µl | Q12983 | RUO | |
Abbexa | BNIP3 | abx320038 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, IHC, IF/ICC | 237.5 | 50 µl | Q12983 | RUO | |
Abbexa | BNIP3 | abx213055 | BCL2 Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2 Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q12983 | RUO | |
Abbexa | BNIP3 | abx027283 | BNIP3 (BH3 Domain Specific) Antibody | Human | Polyclonal | Rabbit | BNIP3 (BH3 Domain Specific) | Unconjugated | ELISA, IHC, IF/ICC | 250 | 80 µl | Q12983 | RUO | |
Abbexa | BNIP3 | abx211746 | BCL2 Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2 Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q12983 | RUO | |
Abbexa | BNIP3 | abx329121 | BCL2 Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2 Interacting Protein 3 (BNIP3) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q12983 | RUO | |
Abbexa | BNIP3 | abx004346 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Antibody | Human | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) | Unconjugated | WB, IHC | 175 | 20 µl | Q12983 | RUO | |
Abbexa | BNIP3L | abx320053 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) Antibody | Human | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) | Unconjugated | ELISA, IHC | 237.5 | 50 µl | O60238 | RUO | |
Abbexa | BNIP3L | abx211524 | BCL2/adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like (BNIP3L) Antibody | Human | Polyclonal | Rabbit | BCL2/adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like (BNIP3L) | Unconjugated | ELISA, IHC | 250 | 50 µl | O60238 | RUO | |
Abbexa | BNIP3L | abx212958 | BCL2/adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like (BNIP3L) Antibody | Human | Polyclonal | Rabbit | BCL2/adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like (BNIP3L) | Unconjugated | ELISA, IHC | 250 | 50 µl | O60238 | RUO | |
Abbexa | BNIP3L | abx004801 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) Antibody | Human | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | O60238 | RUO | |
Abbexa | BNIP3L | abx230929 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) Antibody | Human | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | O60238 | RUO | |
Abbexa | BNIP3 | abx131372 | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Antibody | Rat | Polyclonal | Rabbit | BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | Q9ET45 | RUO | |
Abbexa | BNIP3 | abx171402 | Bcl2/Adenovirus E1B 19 kDa Interacting Protein 3 (BNIP3) Antibody | Rat | Monoclonal | Mouse | Bcl2/Adenovirus E1B 19 kDa Interacting Protein 3 (BNIP3) | Unconjugated | WB, IHC, IF/ICC | 850 | 1 ml | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | BNIP3 | abx650764 | Rat Bcl2/Adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9ET45 | RUO |
Abbexa | BNIP3 | abx692900 | Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) Protein | Human | Recombinant | E. coli | SDS-PAGE | 200 | 10 µg | Q12983 | RUO | |
FineTest | BNIP3 | P4196 | Recombinant Mouse BNIP3 | Mouse | Recombinant | E.Coli | Western Blot,ELISA | 50μg | O55003 | RUO | ||
FineTest | BNIP3L | P0485 | Recombinant Human BNIP3L | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | O60238 | RUO | ||
Abbexa | BNIP3L | abx694049 | Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like (BNIP3L) Protein | Human | Recombinant | E. coli | SDS-PAGE | 962.5 | 100 µg | Q7Z465-1 | RUO |
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