Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for BNIP3
proveedor
Abbexareference
abx257963Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
BCL2 interacting protein 3 (BNIP3) is a pro-apoptotic member of the Bcl-2 family that plays a key role in regulating cell death, particularly in response to cellular stress BNIP3 functions by interacting with anti-apoptotic Bcl-2 family members, promoting mitochondrial outer membrane permeabilization, and facilitating the release of pro-apoptotic factors such as cytochrome c from the mitochondria This release activates the caspase cascade, triggering apoptosis BNIP3 is particularly involved in regulating hypoxia-induced cell death and autophagy, which are essential for cellular adaptation to low oxygen levels and nutrient stress Dysregulation of BNIP3 has been linked to various diseases, including cancer and neurodegenerative disorders, where altered expression of BNIP3 contributes to uncontrolled cell survival, tumor progression, and impaired cellular homeostasis BNIP3's role in mitochondrial function and its involvement in the hypoxic response make it an important factor in regulating cell death and adaptation to environmental stresses
Características del producto
category
ELISA Kits
immunogen target
BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
NIP3,HABON,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
BNIP3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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