Family main features
YWHAG, also known as 14-3-3 protein gamma, is a member of the 14-3-3 family of proteins, which are highly conserved and ubiquitous across eukaryotic species. These proteins play crucial roles in regulating various cellular processes by acting as scaffolds and adaptors that mediate protein-protein interactions. YWHAG is involved in essential cellular functions, including signal transduction, cell cycle regulation, apoptosis, and stress responses. It binds to phosphorylated serine/threonine residues on target proteins, affecting their function, localization, and stability. YWHAG is particularly important in neuronal development and function, contributing to synaptic plasticity and memory formation. Dysregulation of YWHAG is associated with several pathological conditions, including cancer and neurodegenerative diseases.
YWHAH, like other 14-3-3 proteins, has a conserved structure characterized by:
YWHAG is one of the seven mammalian isoforms of the 14-3-3 protein family, which includes β, γ (YWHAG), ε, η, σ, τ, and ζ. Each isoform, while structurally similar, has specific and sometimes overlapping functions in different tissues and cellular contexts.
YWHAG is involved in several critical cellular functions:
Alterations in YWHAG expression or function are associated with several diseases:
YWHAG (14-3-3 protein gamma) is a multifunctional adaptor protein involved in critical cellular processes, including signal transduction, cell cycle regulation, apoptosis, and stress response. Its structure, featuring nine alpha helices and a phosphoserine/threonine-binding groove, enables it to interact with a wide range of phosphorylated target proteins. Dysregulation of YWHAG is linked to various diseases, including cancer and neurodegenerative disorders, underscoring its importance in maintaining cellular homeostasis. ELISA, CLIA, antibodies, and recombinant proteins are essential tools for studying YWHAG, providing insights into its expression, function, and role in disease. Understanding the molecular mechanisms and interactions of YWHAG can provide insights into potential therapeutic targets for these diseases.
14-3-3 protein gamma (YWHAG )
YWHAG, 14-3-3GAMMA, PPP1R170, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, EIEE56
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con YWHAG - 14-3-3 protein gamma
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Esta página contiene 26 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | YWHAG | EH6002 | Human KCIP-1(14-3-3 GAMMA) ELISA Kit | human | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | P61981 | RUO | ||
Abbexa | YWHAG | abx385526 | Human 14-3-3 Protein Gamma (YWHAG) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.16 ng/ml | 687.5 | 96 tests | P61981 | RUO |
Abbexa | YWHAG | abx500018 | Mouse 14-3-3 Protein Gamma (YWHAG) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | P61982 | RUO |
Abbexa | YWHAG | abx500019 | Rat 14-3-3 Protein Gamma (YWHAG) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | P61983 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | YWHAG | FNab00004 | anti- 14-3-3 GAMMA-Specific antibody | human | polyclonal | Rabbit | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | IgG | Unconjugated | ELISA, IHC, IP, WB, IF | 100µg | P61981 | RUO | |
Abbexa | YWHAG | abx137292 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Monoclonal | Mouse | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | 225 | 5 µg | RUO | |||
Abbexa | YWHAG | abx402416 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Monoclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | ELISA, WB, IHC | 287.5 | 50 µl | P61981 | RUO | |
Abbexa | YWHAG | abx313191 | 14-3-3 Protein Gamma (YWHAG) Antibody (FITC) | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | FITC | 162.5 | 20 µg | P61981 | RUO | ||
Abbexa | YWHAG | abx313190 | 14-3-3 Protein Gamma (YWHAG) Antibody (HRP) | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | HRP | ELISA | 162.5 | 20 µg | P61981 | RUO | |
Abbexa | YWHAG | abx313192 | 14-3-3 Protein Gamma (YWHAG) Antibody (Biotin) | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Biotin | ELISA | 162.5 | 20 µg | P61981 | RUO | |
Abbexa | YWHAG | abx122269 | 14-3-3 Protein Gamma (ywhag) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (ywhag) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | YWHAG | abx137538 | 14-3-3 Gamma (YWHAG) Antibody | Human | Monoclonal | Mouse | 14-3-3 Gamma (YWHAG) | 225 | 5 µg | RUO | ||||
Abbexa | YWHAG | abx031810 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P61981 | RUO | |
Abbexa | YWHAG | abx031808 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P61981 | RUO | |
Abbexa | YWHAG | abx241069 | 14-3-3 protein gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 protein gamma (YWHAG) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P61981 | RUO | |
Abbexa | YWHAG | abx013881 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | WB, IHC, IF/ICC | 43.75 | 10 µg | P61981 | RUO | |
Abbexa | YWHAG | abx116386 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P61981 | RUO | |
Abbexa | YWHAG | abx241068 | 14-3-3 protein gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 protein gamma (YWHAG) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P61981 | RUO | |
Abbexa | YWHAG | abx318025 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | ELISA, WB, IHC, IP | 162.5 | 20 µg | P61981 | RUO | |
Abbexa | YWHAG | abx329251 | 14-3-3 protein gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 protein gamma (YWHAG) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P61981 | RUO | |
Abbexa | YWHAG | abx002198 | 14-3-3 Protein Gamma (YWHAG) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Gamma (YWHAG) | Unconjugated | WB, IHC | 175 | 20 µl | P61981 | RUO | |
Abbexa | YWHAG | abx230004 | 14-3-3 GAMMA-Specific Antibody | Human | Polyclonal | Rabbit | 14-3-3 GAMMA-Specific | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 350 | 100 µg | P61981 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | YWHAG | abx073591 | Human 14-3-3 Protein Gamma (YWHAG) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | P61981 | RUO | |
Abbexa | YWHAG | abx682069 | Human 14-3-3 Gamma (YWHAG) Protein | Human | Recombinant | E. coli | Unconjugated | SDS-PAGE | 262.5 | 10 µg | P61981 | RUO |
FineTest | YWHAG | P1760 | Recombinant Human YWHAG | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P61981 | RUO | ||
Abbexa | YWHAG | abx073645 | Human 14-3-3 Protein Gamma (YWHAG) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 2 µg | P61981 | RUO |
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