Human YWHAG (14-3-3 GAMMA) ELISA Kit
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name
Human YWHAG (14-3-3 GAMMA) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH6002
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P61981 |
| Alias | YWHAG, 14-3-3GAMMA, PPP1R170, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, EIEE56, DEE56 |
| Background | Elisa kits for YWHAG |
| Status | RUO |
YWHAG is a key adaptor protein that regulates cellular signaling by interacting with phosphorylated proteins, stabilizing complexes, and controlling their subcellular localization. It participates in pathways such as PI3K/Akt, MAPK, and p53 signaling, where it regulates cell cycle progression, apoptosis, and DNA damage response. YWHAG is highly expressed in neuronal tissues and plays essential roles in synaptic plasticity, neurogenesis, and axonal growth. It also participates in stress response pathways by stabilizing proteins involved in cellular repair and survival. Dysregulation of YWHAG has been implicated in neurodegenerative diseases, including Alzheimer’s and Huntington’s disease, where abnormal interactions lead to protein aggregation and neuronal dysfunction. Additionally, it is overexpressed in various cancers, contributing to tumor progression, resistance to apoptosis, and metastasis. Knockdown studies reveal impaired cell cycle regulation, increased apoptosis, and disrupted neuronal signaling, underscoring its role in maintaining cellular stability and brain function.
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