Rat 14-3-3 Protein Gamma (YWHAG) ELISA Kit

Este producto es parte de YWHAG - 14-3-3 protein gamma
Rat 14-3-3 Protein Gamma (YWHAG) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for YWHAG

proveedor

Abbexa

reference

abx500019

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat 14-3-3 Gamma (YWHAG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat 14-3-3 Protein Gamma concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

YWHAG is a key adaptor protein that regulates cellular signaling by interacting with phosphorylated proteins, stabilizing complexes, and controlling their subcellular localization. It participates in pathways such as PI3K/Akt, MAPK, and p53 signaling, where it regulates cell cycle progression, apoptosis, and DNA damage response. YWHAG is highly expressed in neuronal tissues and plays essential roles in synaptic plasticity, neurogenesis, and axonal growth. It also participates in stress response pathways by stabilizing proteins involved in cellular repair and survival. Dysregulation of YWHAG has been implicated in neurodegenerative diseases, including Alzheimer’s and Huntington’s disease, where abnormal interactions lead to protein aggregation and neuronal dysfunction. Additionally, it is overexpressed in various cancers, contributing to tumor progression, resistance to apoptosis, and metastasis. Knockdown studies reveal impaired cell cycle regulation, increased apoptosis, and disrupted neuronal signaling, underscoring its role in maintaining cellular stability and brain function.

Características del producto

category

ELISA Kits


immunogen target

14-3-3 Protein Gamma (YWHAG)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

YWHAG, 14-3-3GAMMA, PPP1R170, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, EIEE56, DEE56


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

YWHAG


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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