Rat 14-3-3 Protein Gamma (YWHAG) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for YWHAG
proveedor
Abbexareference
abx500019Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat 14-3-3 Gamma (YWHAG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat 14-3-3 Protein Gamma concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
YWHAG is a key adaptor protein that regulates cellular signaling by interacting with phosphorylated proteins, stabilizing complexes, and controlling their subcellular localization. It participates in pathways such as PI3K/Akt, MAPK, and p53 signaling, where it regulates cell cycle progression, apoptosis, and DNA damage response. YWHAG is highly expressed in neuronal tissues and plays essential roles in synaptic plasticity, neurogenesis, and axonal growth. It also participates in stress response pathways by stabilizing proteins involved in cellular repair and survival. Dysregulation of YWHAG has been implicated in neurodegenerative diseases, including Alzheimer’s and Huntington’s disease, where abnormal interactions lead to protein aggregation and neuronal dysfunction. Additionally, it is overexpressed in various cancers, contributing to tumor progression, resistance to apoptosis, and metastasis. Knockdown studies reveal impaired cell cycle regulation, increased apoptosis, and disrupted neuronal signaling, underscoring its role in maintaining cellular stability and brain function.
Características del producto
category
ELISA Kits
immunogen target
14-3-3 Protein Gamma (YWHAG)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
YWHAG, 14-3-3GAMMA, PPP1R170, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, EIEE56, DEE56
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
YWHAG
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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