Transcription factor AP-2-epsilon (TFAP2E) Antibody

Este producto es parte de TFAP2 - Transcription factor AP-2 alpha
Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Transcription factor AP-2-epsilon (TFAP2E) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx346818
tested applications
ELISA, WB

Description

Transcription factor AP-2-epsilon (TFAP2E) Antibody is a Rabbit Polyclonal antibody for the detection of Human TFAP2E.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Transcription factor AP-2-epsilon (TFAP2E)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G chromatography.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6VUC0
Gene ID
339488
OMIM
614428
Alias
AP-2epsilon,AP2E,Activating enhancer-binding protein 2-epsilon
Background
Antibody anti-TFAP2E
Status
RUO

Descripción

TFAP2E is a member of the AP-2 family that regulates gene transcription during embryogenesis, tissue differentiation, and organ development. TFAP2E is expressed in various epithelial and neural tissues during development, where it controls cell proliferation, survival, and differentiation by modulating target genes involved in cell adhesion, apoptosis, and morphogenesis. It has also been implicated in the regulation of neural crest migration, contributing to craniofacial and limb development. In cancer biology, altered TFAP2E expression is associated with tumor progression, particularly in colorectal and gastric cancers, where it regulates Wnt/β-catenin signaling and chemoresistance. Knockout studies reveal developmental abnormalities in neural and epithelial tissues, underscoring its role in transcriptional regulation, tissue-specific gene expression, and developmental homeostasis.

Related Products

FNab08620

TFAP2E antibody

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation(By similarity).

Ver Producto
P1559

Recombinant Human TFAP2E

Ver Producto
abx238620

Transcription Factor AP-2 Epsilon (TFAP2E) Antibody

TFAP2E Antibody is a Rabbit Polyclonal against TFAP2E.

Ver Producto