Transcription Factor AP-2-Delta (TFAP2D) Antibody

Background

TFAP2D is a lesser-characterized member of the AP-2 transcription factor family, primarily involved in the regulation of gene expression during development and differentiation. It binds to target DNA sequences in regulatory regions to control genes involved in neural crest cell formation, epithelial tissue differentiation, and organogenesis. TFAP2D is expressed in embryonic tissues, where it plays a role in cell cycle regulation, apoptosis, and tissue morphogenesis. Its function overlaps with other AP-2 family members, although its specific biological roles remain under investigation. Dysregulation of TFAP2D may contribute to developmental abnormalities and potentially tumorigenesis. Knockdown or loss-of-function studies suggest that TFAP2D is required for proper embryonic patterning, epithelial cell development, and transcriptional control during organ development.