Transcription Factor AP-2-Delta (TFAP2D) Antibody

Este producto es parte de TFAP2 - Transcription factor AP-2 alpha
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416€ (200 µl)

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935106861
info@markelab.com
name
Transcription Factor AP-2-Delta (TFAP2D) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431730
tested applications
P-ELISA, WB, IF/ICC, FCM

Description

TFAP2D Antibody is a Goat Polyclonal antibody against TFAP2D.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Transcription Factor AP-2-Delta (TFAP2D)
Host
Goat
Recommended Dilution
P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IF/ICC, FCM
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
83741, 226896, 301284
NCBI Accession
NP_758438.2
Alias
AP-2delta,TFAP2BL1,Activating enhancer-binding protein 2-delta,Transcription factor AP-2-beta-like 1
Background
Antibody anti-TFAP2D
Status
RUO
Note
Concentration: 0.5 mg/ml -

Descripción

TFAP2D is a lesser-characterized member of the AP-2 transcription factor family, primarily involved in the regulation of gene expression during development and differentiation. It binds to target DNA sequences in regulatory regions to control genes involved in neural crest cell formation, epithelial tissue differentiation, and organogenesis. TFAP2D is expressed in embryonic tissues, where it plays a role in cell cycle regulation, apoptosis, and tissue morphogenesis. Its function overlaps with other AP-2 family members, although its specific biological roles remain under investigation. Dysregulation of TFAP2D may contribute to developmental abnormalities and potentially tumorigenesis. Knockdown or loss-of-function studies suggest that TFAP2D is required for proper embryonic patterning, epithelial cell development, and transcriptional control during organ development.

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