Rat Prokineticin Receptor 1 (PROKR1) ELISA Kit

715€ (96 tests)
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name
Rat Prokineticin Receptor 1 (PROKR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx255941
tested applications
ELISA
Description
Rat Prokineticin Receptor 1 (PROKR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat PKR1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Prokineticin Receptor 1 (PROKR1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8R416 |
| Gene ID | 192648 |
| Alias | PROKR1,GPR73a,VEGFR-1,ZAQ ,GPR73,G-protein coupled receptor ZAQ,G protein-coupled receptor 73 |
| Background | Elisa Kits for: PROKR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
PROKR1 is a G protein-coupled receptor activated by prokineticins, small peptide hormones involved in angiogenesis, inflammation, and tissue homeostasis. PROKR1 couples to Gq and Gi/o proteins, activating phospholipase C (PLC) and modulating calcium signaling, MAPK, and PI3K/Akt pathways. PROKR1 is widely expressed in endothelial cells, immune cells, and various organs, including the gastrointestinal tract, cardiovascular system, and reproductive tissues. It plays a critical role in regulating vascular growth, smooth muscle contraction, and inflammatory responses. In reproduction, PROKR1 is essential for implantation, placental development, and uterine function. Dysregulation of PROKR1 signaling has been linked to infertility, inflammatory diseases, and ischemic conditions, where impaired angiogenesis and inflammation occur. PROKR1 is also implicated in cancer progression, promoting tumor angiogenesis and metastasis. Therapeutic targeting of PROKR1 offers potential in treating reproductive disorders, inflammatory diseases, and cancers involving aberrant vascularization and tissue remodeling.
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