Mouse Prokineticin Receptor 1 (PROKR1) ELISA Kit

Este producto es parte de PROKR - Prokineticin Receptor
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546€ (96 tests)

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935106861
info@markelab.com
name
Mouse Prokineticin Receptor 1 (PROKR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx254355
tested applications
ELISA

Description

Mouse Prokineticin Receptor 1 (PROKR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PKR1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Prokineticin Receptor 1 (PROKR1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
0.1 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9JKL1
Gene ID
58182
Alias
PROKR1,GPR73a,VEGFR-1,ZAQ ,GPR73,G-protein coupled receptor ZAQ,G protein-coupled receptor 73
Background
Elisa kits for PROKR1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

PROKR1 is a G protein-coupled receptor activated by prokineticins, small peptide hormones involved in angiogenesis, inflammation, and tissue homeostasis. PROKR1 couples to Gq and Gi/o proteins, activating phospholipase C (PLC) and modulating calcium signaling, MAPK, and PI3K/Akt pathways. PROKR1 is widely expressed in endothelial cells, immune cells, and various organs, including the gastrointestinal tract, cardiovascular system, and reproductive tissues. It plays a critical role in regulating vascular growth, smooth muscle contraction, and inflammatory responses. In reproduction, PROKR1 is essential for implantation, placental development, and uterine function. Dysregulation of PROKR1 signaling has been linked to infertility, inflammatory diseases, and ischemic conditions, where impaired angiogenesis and inflammation occur. PROKR1 is also implicated in cancer progression, promoting tumor angiogenesis and metastasis. Therapeutic targeting of PROKR1 offers potential in treating reproductive disorders, inflammatory diseases, and cancers involving aberrant vascularization and tissue remodeling.

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