Human Prokineticin Receptor 1 (PROKR1) ELISA Kit

Name: Human Prokineticin Receptor 1 (PROKR1) ELISA Kit
Brand: Abbexa
SKU: abx252986
Price: 546 EUR
Availability: OnlineOnly

Este producto es parte de PROKR - Prokineticin Receptor

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for PROKR1

proveedor

Abbexa

reference

abx252986

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Prokineticin Receptor 1 (PROKR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PKR1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

PROKR1 is a G protein-coupled receptor activated by prokineticins, small peptide hormones involved in angiogenesis, inflammation, and tissue homeostasis. PROKR1 couples to Gq and Gi/o proteins, activating phospholipase C (PLC) and modulating calcium signaling, MAPK, and PI3K/Akt pathways. PROKR1 is widely expressed in endothelial cells, immune cells, and various organs, including the gastrointestinal tract, cardiovascular system, and reproductive tissues. It plays a critical role in regulating vascular growth, smooth muscle contraction, and inflammatory responses. In reproduction, PROKR1 is essential for implantation, placental development, and uterine function. Dysregulation of PROKR1 signaling has been linked to infertility, inflammatory diseases, and ischemic conditions, where impaired angiogenesis and inflammation occur. PROKR1 is also implicated in cancer progression, promoting tumor angiogenesis and metastasis. Therapeutic targeting of PROKR1 offers potential in treating reproductive disorders, inflammatory diseases, and cancers involving aberrant vascularization and tissue remodeling.

Características del producto

immunogen target

Prokineticin Receptor 1 (PROKR1)

reactivity

Human

test range

0.625 ng/ml - 40 ng/ml

sensitivity

0.38 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

PROKR1,GPR73a,VEGFR-1,ZAQ ,GPR73,G-protein coupled receptor ZAQ,G protein-coupled receptor 73

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

PROKR1

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q8TCW9

gene id

https://www.ncbi.nlm.nih.gov/gene/10087

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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