Rat Insulin Receptor Substrate 3 (IRS3) Protein

Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein IRS3
proveedor
Abbexareference
abx168504Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Insulin Receptor Substrate 3 (IRS3) Protein is a recombinant Rat protein expressed in E. coli.
Background
Insulin receptor substrate 3 (IRS3) is part of the IRS family of proteins that play a crucial role in the signaling pathways of insulin and insulin-like growth factors. Acting as a molecular scaffold, IRS3 binds to the activated insulin receptor, undergoing phosphorylation on specific tyrosine residues. This process enables the recruitment of downstream signaling molecules, such as phosphatidylinositol 3-kinase (PI3K) and Grb2, which are involved in metabolic regulation, cellular growth, and survival. IRS3 expression is primarily observed in adipose tissue and liver, suggesting its importance in glucose homeostasis and lipid metabolism. Dysregulation of IRS3 activity has been implicated in conditions such as insulin resistance, obesity, and type 2 diabetes. Research on IRS3 has highlighted its potential as a therapeutic target for enhancing insulin sensitivity in metabolic disorders.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Insulin Receptor Substrate 3 (IRS3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 15.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ser110 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
IRS3
dry ice
No
availability
Shipped within 5-7 working days.
alias
IRS3
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Insulin Receptor Substrate 3 (IRS3) Antibody

proveedor
Abbexareference
abx130421Tested Applications
WB, IHC, IF/ICCreactivity
Ratstatus
RUOclonality
PolyclonalInsulin Receptor Substrate 3 (IRS3) Antibody is a Rabbit Polyclonal against Insulin Receptor Substrate 3 (IRS3).
312€ (100 µl)
Ver másRat Insulin Receptor Substrate 3 (IRS3) ELISA Kit

proveedor
Abbexareference
abx155745Tested Applications
ELISAreactivity
Ratstatus
RUORat Insulin Receptor Substrate 3 (IRS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Insul...
767€ (96 tests)
Ver másRat Insulin Receptor Substrate 3 (IRS3) Protein

proveedor
Abbexareference
abx168504Tested Applications
WB, SDS-PAGEstatus
RUOInsulin Receptor Substrate 3 (IRS3) Protein is a recombinant Rat protein expressed in E. coli.
234€ (10 µg)
Ver más