Rat Insulin Receptor Substrate 3 (IRS3) ELISA Kit

Este producto es parte de IRS -Insulin receptor substrate
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767€ (96 tests)

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935106861
info@markelab.com
name
Rat Insulin Receptor Substrate 3 (IRS3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx155745
tested applications
ELISA

Description

Rat Insulin Receptor Substrate 3 (IRS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Insulin Receptor Substrate 3 (IRS3) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Insulin Receptor Substrate 3 (Insulin Receptor Substrate 3 (IRS3)) (Insulin Receptor Substrate 3 (IRS3))

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Insulin Receptor Substrate 3 (IRS3)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.625 ng/ml - 40 ng/ml
Sensitivity
< 0.23 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
IRS3
Background
Elisa Kits for: IRS3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

Insulin receptor substrate 3 (IRS3) is part of the IRS family of proteins that play a crucial role in the signaling pathways of insulin and insulin-like growth factors. Acting as a molecular scaffold, IRS3 binds to the activated insulin receptor, undergoing phosphorylation on specific tyrosine residues. This process enables the recruitment of downstream signaling molecules, such as phosphatidylinositol 3-kinase (PI3K) and Grb2, which are involved in metabolic regulation, cellular growth, and survival. IRS3 expression is primarily observed in adipose tissue and liver, suggesting its importance in glucose homeostasis and lipid metabolism. Dysregulation of IRS3 activity has been implicated in conditions such as insulin resistance, obesity, and type 2 diabetes. Research on IRS3 has highlighted its potential as a therapeutic target for enhancing insulin sensitivity in metabolic disorders.

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