Rat A-Kinase Anchor Protein 2 (AKAP2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AKAP2
proveedor
Abbexareference
abx501402Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat A-Kinase Anchor Protein 2 (AKAP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat A-kinase anchor protein 2 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
AKAP2, also called AKAP-KL, is a dual-targeting scaffold protein that interacts with PKA, phospholipase C (PLC), and signaling proteins near cellular membranes. AKAP2 is highly expressed in endothelial cells, where it regulates cytoskeletal remodeling, cell adhesion, and vascular homeostasis. It organizes PKA signaling at the plasma membrane to control focal adhesion turnover and actin cytoskeleton dynamics, critical for endothelial barrier function and angiogenesis. AKAP2 interacts with membrane receptors and small GTPases, linking it to signaling pathways that regulate migration, adhesion, and proliferation in vascular tissues. Dysregulation of AKAP2 has been implicated in cardiovascular diseases, as loss of its function disrupts endothelial integrity and angiogenic signaling. Additionally, AKAP2 plays a role in neuronal development and synaptic plasticity, where its cytoskeletal organization supports neurite outgrowth and network formation.
Características del producto
category
ELISA Kits
immunogen target
A-Kinase Anchor Protein 2 (AKAP2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
PALM2AKAP2,KIAA0920, PAKAP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AKAP2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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