Name: Human A-kinase anchor protein 2 (AKAP2) ELISA Kit
Brand: Abbexa
SKU: abx501400
Price: 687.5 EUR
Availability: OnlineOnly

Background

AKAP2, also called AKAP-KL, is a dual-targeting scaffold protein that interacts with PKA, phospholipase C (PLC), and signaling proteins near cellular membranes. AKAP2 is highly expressed in endothelial cells, where it regulates cytoskeletal remodeling, cell adhesion, and vascular homeostasis. It organizes PKA signaling at the plasma membrane to control focal adhesion turnover and actin cytoskeleton dynamics, critical for endothelial barrier function and angiogenesis. AKAP2 interacts with membrane receptors and small GTPases, linking it to signaling pathways that regulate migration, adhesion, and proliferation in vascular tissues. Dysregulation of AKAP2 has been implicated in cardiovascular diseases, as loss of its function disrupts endothelial integrity and angiogenic signaling. Additionally, AKAP2 plays a role in neuronal development and synaptic plasticity, where its cytoskeletal organization supports neurite outgrowth and network formation.

Características del producto

immunogen target

A-kinase anchor protein 2 (AKAP2)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

detection method

Colorimetric

sample type

Serum,Plasma,Tissue homogenates,Other biological fluids

size 1

96 tests

alias

PALM2AKAP2,KIAA0920, PAKAP

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

AKAP2

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q9Y2D5

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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A-Kinase Anchor Protein 2 (AKAP2) Antibody

proveedor

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reference

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Tested Applications

reactivity

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status

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clonality

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A-Kinase Anchoring Protein 2 (AKAP2) Antibody

proveedor

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reference

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Tested Applications

ELISA, WB

reactivity

Human

status

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clonality

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