Kin of IRRE-Like Protein 1 (KIRREL) Antibody

Este producto es parte de KIRREL - kirre like nephrin family adhesion molecule
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Kin of IRRE-Like Protein 1 (KIRREL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146468
tested applications
ELISA, WB

Description

KIRREL Antibody is a Rabbit Polyclonal against KIRREL.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Kin of IRRE-Like Protein 1 (KIRREL)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96J84
Gene ID
55243
NCBI Accession
BC109192
Alias
NEPH1,KIRREL,NPHS23,Nephrin-like protein 1,Kin of irregular chiasm-like protein 1,Kin of IRRE-like protein 1
Background
Antibody anti-KIRREL1
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

KIRREL1, also known as nephrin-like protein 1, is a transmembrane protein primarily expressed in the glomerular podocytes of the kidney, where it plays a crucial role in filtration barrier integrity. It belongs to the immunoglobulin superfamily, featuring Ig-like domains that mediate cell-cell adhesion and interactions with other proteins in the slit diaphragm, a key structure in glomerular filtration. KIRREL1 is critical for maintaining podocyte structure and function. Mutations in KIRREL1 are associated with nephrotic syndrome, a condition characterized by proteinuria and kidney dysfunction. Its role in stabilizing the filtration barrier makes it essential for renal physiology.

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KIRREL Antibody is a Rabbit Polyclonal against KIRREL.

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