Human KIRREL (Kin of IRRE-like protein 1) ELISA Kit
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name
Human KIRREL (Kin of IRRE-like protein 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2240
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q96J84 |
| Alias | NEPH1,KIRREL,NPHS23,Nephrin-like protein 1,Kin of irregular chiasm-like protein 1,Kin of IRRE-like protein 1 |
| Background | Elisa kits for KIRREL1 |
| Status | RUO |
KIRREL1, also known as nephrin-like protein 1, is a transmembrane protein primarily expressed in the glomerular podocytes of the kidney, where it plays a crucial role in filtration barrier integrity. It belongs to the immunoglobulin superfamily, featuring Ig-like domains that mediate cell-cell adhesion and interactions with other proteins in the slit diaphragm, a key structure in glomerular filtration. KIRREL1 is critical for maintaining podocyte structure and function. Mutations in KIRREL1 are associated with nephrotic syndrome, a condition characterized by proteinuria and kidney dysfunction. Its role in stabilizing the filtration barrier makes it essential for renal physiology.
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