Human Transcription Factor AP-2 Epsilon (TFAP2E) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TFAP2E
proveedor
Abbexareference
abx383715Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Transcription Factor AP-2 Epsilon (TFAP2E) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TFAP2E concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TFAP2E is a member of the AP-2 family that regulates gene transcription during embryogenesis, tissue differentiation, and organ development. TFAP2E is expressed in various epithelial and neural tissues during development, where it controls cell proliferation, survival, and differentiation by modulating target genes involved in cell adhesion, apoptosis, and morphogenesis. It has also been implicated in the regulation of neural crest migration, contributing to craniofacial and limb development. In cancer biology, altered TFAP2E expression is associated with tumor progression, particularly in colorectal and gastric cancers, where it regulates Wnt/β-catenin signaling and chemoresistance. Knockout studies reveal developmental abnormalities in neural and epithelial tissues, underscoring its role in transcriptional regulation, tissue-specific gene expression, and developmental homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Transcription Factor AP-2 Epsilon (TFAP2E)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
AP-2epsilon,AP2E,Activating enhancer-binding protein 2-epsilon
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TFAP2E
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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