Human Pro-Gastrin Releasing Peptide (ProGRP) CLIA Kit
845€ (96 tests)
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935106861
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name
Human Pro-Gastrin Releasing Peptide (ProGRP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx490373
tested applications
CLIA
Description
Human Pro-Gastrin Releasing Peptide (ProGRP) Chemiluminescent Immunoassay (CLIA) Kit is a Competitive Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Pro-Gastrin Releasing Peptide (ProGRP) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Competitive |
| Test Range | 3.9 pg/ml - 1000 pg/ml |
| Sensitivity | < 1.6 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | BN,GRP-10,proGRP,preproGRP |
| Background | CLIA Kits ProGRP |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Pro-Gastrin Releasing Peptide (ProGRP) is a precursor protein for gastrin-releasing peptide (GRP), a neuropeptide involved in a variety of physiological processes, including the regulation of gastric acid secretion, smooth muscle contraction, and pancreatic enzyme release. GRP is also known for its role in neural signaling, particularly in the central nervous system, where it modulates stress, memory, and circadian rhythm. ProGRP is a clinically significant biomarker, particularly in the diagnosis and monitoring of small cell lung cancer (SCLC), where elevated levels in serum are associated with disease presence and progression. The stability of ProGRP in circulation makes it a superior biomarker compared to GRP itself, as it provides a more reliable measure for diagnostic purposes. Beyond its use in oncology, ProGRP may play a role in gastrointestinal and neuroendocrine disorders, with its expression linked to cellular proliferation and secretion. Current research focuses on its potential as a therapeutic target in SCLC and other malignancies, as well as its broader role in neuroendocrine signaling pathways.
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