Human ATP Binding Cassette Subfamily D Member 2 (ABCD2) ELISA Kit
715€ (96 tests)
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name
Human ATP Binding Cassette Subfamily D Member 2 (ABCD2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385545
tested applications
ELISA
Description
Human ATP Binding Cassette Subfamily D Member 2 (ABCD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Transporter D2 (ABCD2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP Binding Cassette Subfamily D Member 2 (ABCD2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UBJ2 |
| Gene ID | 225 |
| OMIM | 601081 |
| Alias | ABC39,ALDL1,ALDR,ALDRP |
| Background | Elisa kits for ABCD2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCD2 is a peroxisomal ATP-binding cassette transporter that plays a key role in the import of very-long-chain fatty acids (VLCFAs) and their derivatives into peroxisomes for β-oxidation. It is highly expressed in tissues such as the liver, brain, and adrenal glands, where VLCFA metabolism is essential for cellular function and homeostasis. Structurally, ABCD2 contains nucleotide-binding domains that drive ATP-dependent substrate transport across the peroxisomal membrane. ABCD2 shares functional redundancy with ABCD1, compensating for its loss in certain conditions such as X-linked adrenoleukodystrophy (X-ALD). Dysregulation of ABCD2 expression has been associated with metabolic disorders involving lipid accumulation and peroxisomal dysfunction, highlighting its importance in lipid metabolism and cellular health.
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