F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP)
169€ (20 µg)
169€ (20 µg)
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935106861
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name
F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx346418
tested applications
ELISA
Descripción del producto
F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human CARMIL1.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| OMIM | 609593 |
| Alias | F-actin-uncapping protein LRRC16A,CARMIL1,CARMIL,Leucine-rich repeat-containing protein 16A |
| Availability | Shipped within 5-10 working days. |
| Background | Antibody anti-CARMIL1 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Category | Primary Antibodies |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Dry Ice | No |
| Form | Liquid |
| Host | Rabbit |
| Immunogen Target | F-actin-uncapping protein LRRC16A (CARMIL1) |
| Isotype | IgG |
| Name | F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP) |
| Price | 169 |
| Provider | Abbexa |
| Purification | Purified by Protein G chromatography. |
| Purity | > 95% |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx346418 |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Status | RUO |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Tested Applications | ELISA |
| UniProt ID | Q5VZK9 |
Descripcion del producto en español
Background en español
CARMIL1 is a scaffolding protein that regulates actin dynamics by interacting with capping proteins, the Arp2/3 complex, and myosin-I. It plays a critical role in actin filament assembly and disassembly, essential for cell migration, adhesion, and membrane trafficking. CARMIL1 is required for proper lamellipodia and filopodia formation, contributing to cell shape and motility. Dysregulation of CARMIL1 has been linked to cancer metastasis and immune dysfunction, where altered actin remodeling affects cell invasion and signaling. It also participates in signaling pathways related to integrins and cytoskeletal reorganization, making it a target for therapeutic research in metastatic cancer and immune disorders.
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F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human CARMIL1.
Ver Producto